Gene description for Capg |
Gene name |
capping protein (actin filament), gelsolin-like |
Gene symbol |
Capg |
Other names/aliases |
gCap39 mbh1 |
Species |
Mus musculus |
Database cross references - Capg |
ExoCarta |
ExoCarta_12332 |
Entrez Gene |
12332 |
Capg identified in exosomes derived from the following tissue/cell type |
Mast cells
|
17486113
|
Microglia
|
16081791
|
Gene ontology annotations for Capg |
|
Experiment description of studies that identified Capg in exosomes |
1 |
Experiment ID |
15 |
ISEV standards |
✔
EM
|
EV Biophysical techniques |
✘
|
EV Cytosolic markers |
✔
CD63
|
EV Membrane markers |
✘
|
EV Negative markers |
✘
|
EV Particle analysis
|
|
Identified molecule |
protein
|
Identification method |
Mass spectrometry
|
PubMed ID |
17486113
|
Organism |
Mus musculus Homo sapiens |
Experiment description |
Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells. |
Authors |
Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO |
Journal name |
NCB
|
Publication year |
2007 |
Sample |
Mast cells |
Sample name |
MC9 Bone marrow-derived mast cells HMC-1 |
Isolation/purification methods |
Filtration Ultracentrifugation Sucrose density gradient |
Flotation density |
1.11-1.21 g/mL
|
Molecules identified in the study |
Protein mRNA miRNA |
Methods used in the study |
Mass spectrometry [MALDI TOF] Western blotting Microarray miRCURY LNA Array |
|
|
2 |
Experiment ID |
14 |
ISEV standards |
✔
EM
|
EV Biophysical techniques |
✔
RAB7|RAB11
|
EV Cytosolic markers |
✔
CD9|CD63|LAMP1|LAMP2
|
EV Membrane markers |
✔
DNM
|
EV Negative markers |
✘
|
EV Particle analysis
|
|
Identified molecule |
protein
|
Identification method |
Mass spectrometry
|
PubMed ID |
16081791
|
Organism |
Mus musculus |
Experiment description |
Proteomic analysis of microglia-derived exosomes: metabolic role of the aminopeptidase CD13 in neuropeptide catabolism. |
Authors |
Potolicchio I, Carven GJ, Xu X, Stipp C, Riese RJ, Stern LJ, Santambrogio L |
Journal name |
JIMMU
|
Publication year |
2005 |
Sample |
Microglia |
Sample name |
N9 |
Isolation/purification methods |
Differential centrifugation Sucrose density gradient |
Flotation density |
1.15 g/mL
|
Molecules identified in the study |
Protein |
Methods used in the study |
Mass spectrometry [LCQ DECA XP] Western blotting |
|
|
Protein-protein interactions for Capg |
|
Protein Interactor |
ExoCarta ID |
Identification method |
PubMed |
Species |
No interactions are found.
|
|
Pathways in which Capg is involved |
No pathways found
|
|
|