Gene description for Capn6
Gene name calpain 6
Gene symbol Capn6
Other names/aliases -
Species Mus musculus
 Database cross references - Capn6
ExoCarta ExoCarta_12338
Entrez Gene 12338
UniProt O35646  
 Capn6 identified in exosomes derived from the following tissue/cell type
Fibroblasts 23260141    
 Gene ontology annotations for Capn6
Molecular Function
    calcium-dependent cysteine-type endopeptidase activity GO:0004198 IBA
    microtubule binding GO:0008017 IDA
    protein binding GO:0005515 IPI
Biological Process
    regulation of cytoskeleton organization GO:0051493 IMP
    microtubule bundle formation GO:0001578 IMP
    proteolysis GO:0006508 IBA
Subcellular Localization
    perinuclear region of cytoplasm GO:0048471 ISO
    cytoskeleton GO:0005856 IEA
    spindle microtubule GO:0005876 ISO
    cytoplasm GO:0005737 IBA
    intracellular GO:0005622 IEA
    microtubule GO:0005874 IDA
 Experiment description of studies that identified Capn6 in exosomes
Experiment ID 210
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23260141    
Organism Mus musculus
Experiment description Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration.
Authors Luga V, Zhang L, Viloria-Petit AM, Ogunjimi AA, Inanlou MR, Chiu E, Buchanan M, Hosein AN, Basik M, Wrana JL.
Journal name Cell
Publication year 2012
Sample Fibroblasts
Sample name Normal-Fibroblasts (L cells)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Capn6
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Capn6 is involved
No pathways found

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