Gene description for Car2
Gene name	carbonic anhydrase 2
Gene symbol	Car2
Other names/aliases	AI131712 CAII Ca2 Car-2 Ltw-5 Lvtw-5
Species	Mus musculus
Database cross references - Car2
ExoCarta	ExoCarta_12349
Vesiclepedia	VP_12349
Entrez Gene	12349
UniProt	P00920
Car2 identified in sEVs derived from the following tissue/cell type
Oligodendrocytes	21136642

Gene ontology annotations for Car2

Molecular Function     arylesterase activity GO:0004064 IEA     arylesterase activity GO:0004064 ISO     carbonate dehydratase activity GO:0004089 IBA     carbonate dehydratase activity GO:0004089 IDA     carbonate dehydratase activity GO:0004089 IMP     carbonate dehydratase activity GO:0004089 ISO     protein binding GO:0005515 IPI     zinc ion binding GO:0008270 IEA     zinc ion binding GO:0008270 ISO     cyanamide hydratase activity GO:0018820 IEA Biological Process     morphogenesis of an epithelium GO:0002009 IMP     regulation of pH GO:0006885 IC     carbon dioxide transport GO:0015670 IBA     carbon dioxide transport GO:0015670 IC     carbon dioxide transport GO:0015670 IMP     positive regulation of synaptic transmission, GABAergic GO:0032230 IGI     positive regulation of cellular pH reduction GO:0032849 IMP     positive regulation of cellular pH reduction GO:0032849 ISO     angiotensin-activated signaling pathway GO:0038166 ISO     angiotensin-activated signaling pathway GO:0038166 ISS     regulation of monoatomic anion transport GO:0044070 ISO     regulation of monoatomic anion transport GO:0044070 ISS     positive regulation of osteoclast differentiation GO:0045672 ISO     positive regulation of bone resorption GO:0045780 ISO     secretion GO:0046903 IMP     regulation of intracellular pH GO:0051453 IBA     regulation of intracellular pH GO:0051453 IMP     neuron cellular homeostasis GO:0070050 IMP     positive regulation of dipeptide transmembrane transport GO:2001150 IMP     regulation of chloride transport GO:2001225 IMP Subcellular Localization     extracellular space GO:0005615 ISO     cytoplasm GO:0005737 IBA     cytoplasm GO:0005737 ISO     cytoplasm GO:0005737 ISS     cytosol GO:0005829 IDA     plasma membrane GO:0005886 IBA     plasma membrane GO:0005886 ISO     plasma membrane GO:0005886 ISS     microvillus GO:0005902 ISO     basolateral plasma membrane GO:0016323 ISO     axon GO:0030424 ISO     myelin sheath GO:0043209 HDA     myelin sheath GO:0043209 IDA     apical part of cell GO:0045177 IBA     apical part of cell GO:0045177 IEA     apical part of cell GO:0045177 ISO