Gene description for Ccni
Gene name cyclin I
Gene symbol Ccni
Other names/aliases -
Species Mus musculus
 Database cross references - Ccni
ExoCarta ExoCarta_12453
Vesiclepedia VP_12453
Entrez Gene 12453
UniProt Q9Z2V9  
 Ccni identified in sEVs derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Ccni
Molecular Function
    cyclin-dependent protein serine/threonine kinase regulator activity GO:0016538 IBA
    cyclin-dependent protein serine/threonine kinase regulator activity GO:0016538 ISS
Biological Process
    G1/S transition of mitotic cell cycle GO:0000082 IBA
    regulation of cell cycle GO:0051726 TAS
Subcellular Localization
    cyclin-dependent protein kinase holoenzyme complex GO:0000307 IBA
    nucleus GO:0005634 IBA
    cytoplasm GO:0005737 IBA
 Experiment description of studies that identified Ccni in sEVs
1
Experiment ID 15
MISEV standards
EM
Biophysical techniques
CD63
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors "Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO"
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Ccni
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Ccni is involved
No pathways found





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