Gene description for Entpd2
Gene name ectonucleoside triphosphate diphosphohydrolase 2
Gene symbol Entpd2
Other names/aliases Cd39l1
NTPDase2
Species Mus musculus
 Database cross references - Entpd2
ExoCarta ExoCarta_12496
Vesiclepedia VP_12496
Entrez Gene 12496
UniProt O55026  
 Entpd2 identified in sEVs derived from the following tissue/cell type
Mov neuroglial cells 15210972    
 Gene ontology annotations for Entpd2
Molecular Function
    GDP phosphatase activity GO:0004382 IBA
    protein binding GO:0005515 IPI
    ATP binding GO:0005524 IEA
    ATP hydrolysis activity GO:0016887 ISO
    nucleoside diphosphate phosphatase activity GO:0017110 IDA
    ribonucleoside triphosphate phosphatase activity GO:0017111 IBA
    ribonucleoside triphosphate phosphatase activity GO:0017111 IDA
    identical protein binding GO:0042802 ISO
    ADP phosphatase activity GO:0043262 ISO
    UDP phosphatase activity GO:0045134 IBA
Biological Process
    G protein-coupled receptor signaling pathway GO:0007186 IDA
    nucleoside diphosphate catabolic process GO:0009134 IBA
    purine ribonucleoside diphosphate catabolic process GO:0009181 IDA
    platelet activation GO:0030168 IDA
    cellular response to interleukin-6 GO:0071354 ISO
Subcellular Localization
    basement membrane GO:0005604 IDA
    plasma membrane GO:0005886 IBA
    plasma membrane GO:0005886 IDA
    cell surface GO:0009986 ISO
    cell projection membrane GO:0031253 ISO
    cell body GO:0044297 ISO
 Experiment description of studies that identified Entpd2 in sEVs
1
Experiment ID 39
MISEV standards
IEM
Biophysical techniques
TSG101|HSC70|FLOT1
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 15210972    
Organism Mus musculus
Experiment description Cells release prions in association with exosomes.
Authors "Fevrier B, Vilette D, Archer F, Loew D, Faigle W, Vidal M, Laude H, Raposo G"
Journal name PNAS
Publication year 2004
Sample Mov neuroglial cells
Sample name Mov neuroglial cell
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.14 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QSTAR]
Western blotting
Immunoelectron Microscopy
 Protein-protein interactions for Entpd2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Lnx1  
Affinity Capture-MS Mus musculus
View the network image/svg+xml



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