Gene description for Cd48
Gene name CD48 antigen
Gene symbol Cd48
Other names/aliases AI449234
AW610730
BCM1
BLAST
BLAST-1
BLAST1
Bcm-1
MEM-102
SLAMF2
Sgp-60
Species Mus musculus
 Database cross references - Cd48
ExoCarta ExoCarta_12506
Vesiclepedia VP_12506
Entrez Gene 12506
UniProt P18181  
 Cd48 identified in exosomes derived from the following tissue/cell type
Colon cancer cells 37309723    
T-cell lymphoma cells 37309723    
 Gene ontology annotations for Cd48
Molecular Function
    receptor activity GO:0004872 IEA
    antigen binding GO:0003823 ISO
    protein binding GO:0005515 IPI
Biological Process
    mast cell activation GO:0045576 ISO
    signal transduction GO:0007165 IDA
    T cell activation GO:0042110 IDA
Subcellular Localization
    extracellular exosome GO:0070062 ISO
    plasma membrane GO:0005886 ISO
    membrane GO:0016020 ISO
    protein complex GO:0043234 ISO
    membrane raft GO:0045121 ISO
    anchored component of plasma membrane GO:0046658 ISO
    external side of plasma membrane GO:0009897 IDA
    anchored component of membrane GO:0031225 IEA
    integral component of membrane GO:0016021 IEA
 Experiment description of studies that identified Cd48 in exosomes
1
Experiment ID 907
MISEV standards
✔
EM
EV Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
EV Enriched markers
✔
HSPA5
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S.
Journal name Proteomics
Publication year 2023
Sample Colon cancer cells
Sample name C26
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
2
Experiment ID 908
MISEV standards
✔
EM
EV Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
EV Enriched markers
✔
HSPA5
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S.
Journal name Proteomics
Publication year 2023
Sample T-cell lymphoma cells
Sample name EL4
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for Cd48
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Cd48 is involved
PathwayEvidenceSource
Cell surface interactions at the vascular wall IEA Reactome





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here