Gene description for Cd80
Gene name CD80 antigen
Gene symbol Cd80
Other names/aliases B71
Cd28l
Ly-53
Ly53
MIC17
TSA1
Species Mus musculus
 Database cross references - Cd80
ExoCarta ExoCarta_12519
Entrez Gene 12519
UniProt Q00609  
 Cd80 identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Cd80
Molecular Function
    protein binding GO:0005515 IPI
Biological Process
    positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 ISO
    T cell costimulation GO:0031295 IDA
    positive regulation of alpha-beta T cell proliferation GO:0046641 IDA
    positive regulation of T cell proliferation GO:0042102 ISO
    cellular response to lipopolysaccharide GO:0071222 IDA
Subcellular Localization
    external side of plasma membrane GO:0009897 IDA
    integral component of membrane GO:0016021 IEA
    membrane GO:0016020 IEA
    cell surface GO:0009986 ISO
 Experiment description of studies that identified Cd80 in exosomes
1
Experiment ID 15
ISEV standards
✔
EM
EV Biophysical techniques
✘ EV Cytosolic markers
✔
CD63
EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Cd80
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here