Gene description for Cd86
Gene name	CD86 antigen
Gene symbol	Cd86
Other names/aliases	B7 B7-2 B7.2 B70 CLS1 Cd28l2 ETC-1 Ly-58 Ly58 MB7 MB7-2 TS/A-2
Species	Mus musculus
Database cross references - Cd86
ExoCarta	ExoCarta_12524
Vesiclepedia	VP_12524
Entrez Gene	12524
UniProt	P42082
Cd86 identified in sEVs derived from the following tissue/cell type
Mast cells	11145662
Mast cells	11306949

Gene ontology annotations for Cd86

Molecular Function     signaling receptor binding GO:0005102 ISO     protein binding GO:0005515 IPI     receptor ligand activity GO:0048018 ISO Biological Process     toll-like receptor signaling pathway GO:0002224 IDA     adaptive immune response GO:0002250 IEA     positive regulation of immunoglobulin production GO:0002639 IDA     negative regulation of T cell anergy GO:0002668 ISO     immune response GO:0006955 IBA     cell surface receptor signaling pathway GO:0007166 IBA     T cell costimulation GO:0031295 IBA     toll-like receptor 3 signaling pathway GO:0034138 IMP     positive regulation of T cell proliferation GO:0042102 IBA     positive regulation of T cell proliferation GO:0042102 IGI     positive regulation of T cell proliferation GO:0042102 ISO     positive regulation of activated T cell proliferation GO:0042104 ISO     T cell activation GO:0042110 ISO     B cell activation GO:0042113 IDA     B cell activation GO:0042113 IDA     negative regulation of T cell proliferation GO:0042130 IBA     defense response to virus GO:0051607 IDA     cellular response to lipopolysaccharide GO:0071222 IBA     cellular response to lipopolysaccharide GO:0071222 IDA     positive regulation of non-canonical NF-kappaB signal transduction GO:1901224 IDA Subcellular Localization     plasma membrane GO:0005886 ISO     external side of plasma membrane GO:0009897 IBA     external side of plasma membrane GO:0009897 IDA     cell surface GO:0009986 ISO     centriolar satellite GO:0034451 ISO     intracellular membrane-bounded organelle GO:0043231 IDA     extracellular exosome GO:0070062 ISO