Gene description for Ovgp1
Gene name oviductal glycoprotein 1
Gene symbol Ovgp1
Other names/aliases 120kDa
AU016433
AU019448
Chit5
MOGP
OGP
muc9
Species Mus musculus
 Database cross references - Ovgp1
ExoCarta ExoCarta_12659
Entrez Gene 12659
UniProt Q62010  
 Ovgp1 identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Ovgp1
Molecular Function
    chitinase activity GO:0004568 IBA
    hydrolase activity, hydrolyzing O-glycosyl compounds GO:0004553 IEA
    chitin binding GO:0008061 IBA
Biological Process
    chitin catabolic process GO:0006032 IBA
    carbohydrate metabolic process GO:0005975 IEA
    negative regulation of binding of sperm to zona pellucida GO:2000360 IMP
    single fertilization GO:0007338 IEA
Subcellular Localization
    perivitelline space GO:0098595 IDA
    egg coat GO:0035805 IDA
    cytoplasmic vesicle GO:0031410 IEA
 Experiment description of studies that identified Ovgp1 in exosomes
1
Experiment ID 15
ISEV standards
✔
EM
EV Biophysical techniques
✘ EV Cytosolic markers
✔
CD63
EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Ovgp1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Ovgp1 is involved
PathwayEvidenceSource
Interaction With The Zona Pellucida IEA Reactome





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