Gene description for RPTN
Gene name repetin
Gene symbol RPTN
Other names/aliases -
Species Homo sapiens
 Database cross references - RPTN
ExoCarta ExoCarta_126638
Entrez Gene 126638
HGNC 26809
MIM 613259
UniProt Q6XPR3  
 RPTN identified in exosomes derived from the following tissue/cell type
Hepatocellular carcinoma cells 26054723    
 Gene ontology annotations for RPTN
Molecular Function
    calcium ion binding GO:0005509 IEA
Subcellular Localization
    proteinaceous extracellular matrix GO:0005578 IEA
    cornified envelope GO:0001533 IEA
 Experiment description of studies that identified RPTN in exosomes
1
Experiment ID 235
ISEV standards
EM
EV Biophysical techniques
TSG101|Alix|HSC70|GAPDH
EV Cytosolic markers
EV Membrane markers
HSP90B1
EV Negative markers
qNano
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
 Protein-protein interactions for RPTN
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which RPTN is involved
No pathways found





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