Gene description for Cpne6
Gene name copine VI
Gene symbol Cpne6
Other names/aliases AU067659
BB076446
Species Mus musculus
 Database cross references - Cpne6
ExoCarta ExoCarta_12891
Entrez Gene 12891
UniProt Q9Z140  
 Cpne6 identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Cpne6
Molecular Function
    phosphatidylserine binding GO:0001786 IDA
Biological Process
    positive regulation of dendrite extension GO:1903861 ISO
Subcellular Localization
    extracellular exosome GO:0070062 ISO
    dendrite GO:0030425 IDA
    membrane GO:0016020 IDA
    axon GO:0030424 IDA
 Experiment description of studies that identified Cpne6 in exosomes
1
Experiment ID 15
ISEV standards
✔
EM
EV Biophysical techniques
✘ EV Cytosolic markers
✔
CD63
EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Cpne6
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Cpne6 is involved
PathwayEvidenceSource
Glycerophospholipid biosynthesis IEA Reactome





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here