Gene description for CMPK2
Gene name cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
Gene symbol CMPK2
Other names/aliases TMPK2
TYKi
UMP-CMPK2
Species Homo sapiens
 Database cross references - CMPK2
ExoCarta ExoCarta_129607
Vesiclepedia VP_129607
Entrez Gene 129607
HGNC 27015
MIM 611787
UniProt Q5EBM0  
 CMPK2 identified in sEVs derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for CMPK2
Molecular Function
    (d)CMP kinase activity GO:0004127 IBA
    (d)CMP kinase activity GO:0004127 IDA
    nucleoside diphosphate kinase activity GO:0004550 IBA
    nucleoside diphosphate kinase activity GO:0004550 IDA
    thymidylate kinase activity GO:0004798 IBA
    ATP binding GO:0005524 IEA
    UMP kinase activity GO:0033862 IDA
    CMP kinase activity GO:0036430 IEA
    dCMP kinase activity GO:0036431 IEA
Biological Process
    dUDP biosynthetic process GO:0006227 IBA
    dTDP biosynthetic process GO:0006233 IBA
    dTTP biosynthetic process GO:0006235 IBA
    nucleoside monophosphate phosphorylation GO:0046940 IEA
    cellular response to lipopolysaccharide GO:0071222 IEA
Subcellular Localization
    nucleoplasm GO:0005654 IDA
    cytoplasm GO:0005737 IBA
    mitochondrion GO:0005739 HTP
    mitochondrion GO:0005739 IBA
    mitochondrion GO:0005739 IDA
 Experiment description of studies that identified CMPK2 in sEVs
1
Experiment ID 217
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|CD81|CD9|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for CMPK2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which CMPK2 is involved
No pathways found





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