Gene description for Cyp2c38
Gene name cytochrome P450, family 2, subfamily c, polypeptide 38
Gene symbol Cyp2c38
Other names/aliases -
Species Mus musculus
 Database cross references - Cyp2c38
ExoCarta ExoCarta_13097
Vesiclepedia VP_13097
Entrez Gene 13097
UniProt P56655  
 Cyp2c38 identified in sEVs derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Cyp2c38
Molecular Function
    monooxygenase activity GO:0004497 ISO
    iron ion binding GO:0005506 IEA
    arachidonate epoxygenase activity GO:0008392 ISO
    steroid hydroxylase activity GO:0008395 ISO
    retinoic acid 4-hydroxylase activity GO:0008401 ISO
    arachidonate 14,15-epoxygenase activity GO:0008404 IDA
    arachidonate 11,12-epoxygenase activity GO:0008405 IDA
    oxidoreductase activity GO:0016491 ISO
    oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen GO:0016712 IBA
    oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen GO:0016712 IEA
    enzyme binding GO:0019899 ISO
    heme binding GO:0020037 IBA
    heme binding GO:0020037 IEA
    heme binding GO:0020037 ISO
    caffeine oxidase activity GO:0034875 ISO
    estrogen 16-alpha-hydroxylase activity GO:0101020 ISO
    long-chain fatty acid omega-1 hydroxylase activity GO:0120319 ISO
Biological Process
    organic acid metabolic process GO:0006082 IBA
    xenobiotic metabolic process GO:0006805 IBA
    arachidonate metabolic process GO:0019369 IDA
    arachidonate metabolic process GO:0019369 IEA
Subcellular Localization
    cytoplasm GO:0005737 IBA
    endoplasmic reticulum membrane GO:0005789 IEA
    plasma membrane GO:0005886 ISO
    intracellular membrane-bounded organelle GO:0043231 IBA
    intracellular membrane-bounded organelle GO:0043231 ISO
 Experiment description of studies that identified Cyp2c38 in sEVs
1
Experiment ID 15
MISEV standards
✔
EM
Biophysical techniques
✔
CD63
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors "Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO"
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Cyp2c38
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Cyp2c38 is involved
No pathways found





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