Gene description for ADM
Gene name	adrenomedullin
Gene symbol	ADM
Other names/aliases	AM PAMP
Species	Homo sapiens
Database cross references - ADM
ExoCarta	ExoCarta_133
Entrez Gene	133
HGNC	259
MIM	103275
UniProt	P35318
ADM identified in exosomes derived from the following tissue/cell type
Hepatocellular carcinoma cells	26054723

Gene ontology annotations for ADM

Molecular Function     hormone activity GO:0005179 IEA     adrenomedullin receptor binding GO:0031700 IEA     receptor binding GO:0005102 TAS     protein binding GO:0005515 IPI Biological Process     response to hypoxia GO:0001666 IEA     positive regulation of vasculogenesis GO:2001214 IEA     cell-cell signaling GO:0007267 TAS     response to wounding GO:0009611 IEA     neuron projection regeneration GO:0031102 IEA     blood circulation GO:0008015 TAS     androgen metabolic process GO:0008209 IEA     response to insulin GO:0032868 IEA     heart development GO:0007507 IEA     developmental growth GO:0048589 IEA     positive regulation of cell proliferation GO:0008284 IEA     vasculogenesis GO:0001570 IDA     positive regulation of vasodilation GO:0045909 IEA     female pregnancy GO:0007565 IEA     response to lipopolysaccharide GO:0032496 IEA     spongiotrophoblast layer development GO:0060712 IEA     aging GO:0007568 IEA     signal transduction GO:0007165 TAS     negative regulation of vasoconstriction GO:0045906 IDA     odontogenesis of dentin-containing tooth GO:0042475 IEA     negative regulation of vascular permeability GO:0043116 IEA     G-protein coupled receptor internalization GO:0002031 IDA     positive regulation of angiogenesis GO:0045766 IEA     vascular smooth muscle cell development GO:0097084 IEA     hormone secretion GO:0046879 IEA     receptor internalization GO:0031623 IDA     branching involved in labyrinthine layer morphogenesis GO:0060670 IEA     organ regeneration GO:0031100 IEA     positive regulation of apoptotic process GO:0043065 IEA     response to starvation GO:0042594 IEA     cAMP biosynthetic process GO:0006171 IDA     positive regulation of cytosolic calcium ion concentration GO:0007204 IEA     cAMP-mediated signaling GO:0019933 IEA     regulation of the force of heart contraction GO:0002026 IEA     progesterone biosynthetic process GO:0006701 TAS     neural tube closure GO:0001843 IEA     positive regulation of heart rate GO:0010460 IEA     negative regulation of cell proliferation GO:0008285 IEA     response to glucocorticoid GO:0051384 IEA     response to cold GO:0009409 IEA     positive regulation of cAMP biosynthetic process GO:0030819 IDA Subcellular Localization     cytosol GO:0005829 IEA     cytoplasm GO:0005737 IDA     extracellular space GO:0005615 IDA     extracellular region GO:0005576 TAS