Gene description for Dll1
Gene name	delta-like 1 (Drosophila)
Gene symbol	Dll1
Other names/aliases	Delta1
Species	Mus musculus
Database cross references - Dll1
ExoCarta	ExoCarta_13388
Vesiclepedia	VP_13388
Entrez Gene	13388
UniProt	Q61483
Dll1 identified in sEVs derived from the following tissue/cell type
Mast cells	17486113

Gene ontology annotations for Dll1

Molecular Function     Notch binding GO:0005112 IBA     Notch binding GO:0005112 IPI     Notch binding GO:0005112 ISO     calcium ion binding GO:0005509 IEA     protein binding GO:0005515 IPI     Tat protein binding GO:0030957 IEA     Tat protein binding GO:0030957 ISO     receptor ligand activity GO:0048018 IEA     receptor ligand activity GO:0048018 ISO     scaffold protein binding GO:0097110 IPI Biological Process     in utero embryonic development GO:0001701 NAS     somitogenesis GO:0001756 IGI     somitogenesis GO:0001756 IMP     somite specification GO:0001757 IMP     heart looping GO:0001947 IMP     inhibition of neuroepithelial cell differentiation GO:0002085 IMP     marginal zone B cell differentiation GO:0002315 IMP     type B pancreatic cell development GO:0003323 IMP     Notch signaling pathway GO:0007219 IBA     Notch signaling pathway GO:0007219 IEP     Notch signaling pathway GO:0007219 IMP     Notch signaling pathway GO:0007219 ISO     Notch signaling pathway GO:0007219 TAS     cell-cell signaling GO:0007267 IDA     determination of left/right symmetry GO:0007368 IMP     compartment pattern specification GO:0007386 IMP     nervous system development GO:0007399 NAS     regulation of blood pressure GO:0008217 IMP     positive regulation of cell population proliferation GO:0008284 IMP     negative regulation of cell population proliferation GO:0008285 IMP     animal organ morphogenesis GO:0009887 NAS     auditory receptor cell fate commitment GO:0009912 NAS     proximal/distal pattern formation GO:0009954 IMP     positive regulation of gene expression GO:0010628 IMP     positive regulation of gene expression GO:0010628 ISO     astrocyte development GO:0014002 IMP     regulation of somitogenesis GO:0014807 IMP     spinal cord development GO:0021510 IMP     cerebellar molecular layer formation GO:0021688 IMP     cerebellar Purkinje cell layer structural organization GO:0021693 IMP     myeloid cell differentiation GO:0030099 IDA     regulation of cell adhesion GO:0030155 IMP     neuron differentiation GO:0030182 IMP     negative regulation of epithelial cell differentiation GO:0030857 IMP     regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 IMP     negative regulation of interleukin-10 production GO:0032693 IEA     negative regulation of interleukin-10 production GO:0032693 ISO     negative regulation of glial cell apoptotic process GO:0034351 IMP     organ growth GO:0035265 IMP     regulation of growth GO:0040008 IMP     hemocyte differentiation GO:0042386 IDA     inner ear morphogenesis GO:0042472 NAS     odontogenesis of dentin-containing tooth GO:0042475 NAS     inner ear auditory receptor cell differentiation GO:0042491 IMP     inner ear auditory receptor cell differentiation GO:0042491 NAS     negative regulation of cell differentiation GO:0045596 IMP     negative regulation of cell differentiation GO:0045596 IMP     negative regulation of epidermal cell differentiation GO:0045605 IMP     negative regulation of inner ear auditory receptor cell differentiation GO:0045608 IMP     negative regulation of hemocyte differentiation GO:0045611 IDA     negative regulation of myeloid cell differentiation GO:0045638 IDA     negative regulation of myoblast differentiation GO:0045662 IMP     negative regulation of neuron differentiation GO:0045665 IMP     negative regulation of neuron differentiation GO:0045665 IMP     negative regulation of Notch signaling pathway GO:0045746 IBA     positive regulation of Notch signaling pathway GO:0045747 IDA     positive regulation of Notch signaling pathway GO:0045747 IDA     positive regulation of Notch signaling pathway GO:0045747 IMP     positive regulation of Notch signaling pathway GO:0045747 ISO     positive regulation of endocytosis GO:0045807 IDA     positive regulation of transcription by RNA polymerase II GO:0045944 IMP     lateral inhibition GO:0046331 IDA     lateral inhibition GO:0046331 IMP     skeletal muscle tissue growth GO:0048630 IMP     regulation of skeletal muscle tissue growth GO:0048631 IMP     positive regulation of skeletal muscle tissue growth GO:0048633 IMP     neuron fate specification GO:0048665 IDA     inner ear development GO:0048839 IMP     regulation of neurogenesis GO:0050767 IMP     regulation of neurogenesis GO:0050767 IMP     regulation of cell division GO:0051302 IMP     retina development in camera-type eye GO:0060041 IMP     retina morphogenesis in camera-type eye GO:0060042 IMP     neuroepithelial cell differentiation GO:0060563 IMP     Notch signaling pathway involved in arterial endothelial cell fate commitment GO:0060853 IMP     left/right axis specification GO:0070986 IMP     nephron development GO:0072006 IMP     proximal tubule development GO:0072014 IEP     loop of Henle development GO:0072070 IEP     clathrin-dependent endocytosis GO:0072583 ISO     clathrin-dependent endocytosis GO:0072583 ISS     energy homeostasis GO:0097009 IMP     endothelial tip cell fate specification GO:0097102 IMP     neuronal stem cell population maintenance GO:0097150 IMP     skin epidermis development GO:0098773 IMP     regulation of vascular endothelial growth factor signaling pathway GO:1900746 IMP     positive regulation of sprouting angiogenesis GO:1903672 IMP     negative regulation of cardiac muscle cell differentiation GO:2000726 IMP Subcellular Localization     nucleus GO:0005634 IEA     plasma membrane GO:0005886 IBA     plasma membrane GO:0005886 IDA     plasma membrane GO:0005886 TAS     adherens junction GO:0005912 IDA     apical plasma membrane GO:0016324 IDA     cytoplasmic vesicle GO:0031410 IDA     membrane raft GO:0045121 IDA