Gene description for Ecel1
Gene name endothelin converting enzyme-like 1
Gene symbol Ecel1
Other names/aliases DINE
Species Mus musculus
 Database cross references - Ecel1
ExoCarta ExoCarta_13599
Entrez Gene 13599
UniProt Q9JMI0  
 Ecel1 identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Ecel1
Molecular Function
    peptidase activity GO:0008233 IEA
    metalloendopeptidase activity GO:0004222 IDA
    hydrolase activity GO:0016787 IEA
    metallopeptidase activity GO:0008237 IEA
    metal ion binding GO:0046872 IEA
Biological Process
    proteolysis GO:0006508 IDA
    neuropeptide signaling pathway GO:0007218 ISO
    intracellular signal transduction GO:0035556 ISO
    respiratory system process GO:0003016 IMP
Subcellular Localization
    integral component of membrane GO:0016021 IEA
    intracellular GO:0005622 ISO
    integral component of plasma membrane GO:0005887 ISS
    membrane GO:0016020 IEA
 Experiment description of studies that identified Ecel1 in exosomes
Experiment ID 15
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
Isolation/purification methods Filtration
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
 Protein-protein interactions for Ecel1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Ecel1 is involved
No pathways found

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