Gene description for Ecel1
Gene name endothelin converting enzyme-like 1
Gene symbol Ecel1
Other names/aliases DINE
xce
Species Mus musculus
 Database cross references - Ecel1
ExoCarta ExoCarta_13599
Vesiclepedia VP_13599
Entrez Gene 13599
UniProt Q9JMI0  
 Ecel1 identified in sEVs derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Ecel1
Molecular Function
    metalloendopeptidase activity GO:0004222 IBA
    metalloendopeptidase activity GO:0004222 IDA
    metal ion binding GO:0046872 IEA
Biological Process
    respiratory system process GO:0003016 IMP
    proteolysis GO:0006508 IEA
    neuropeptide signaling pathway GO:0007218 ISO
    protein processing GO:0016485 IBA
    intracellular signal transduction GO:0035556 ISO
Subcellular Localization
    plasma membrane GO:0005886 IBA
    plasma membrane GO:0005886 ISS
 Experiment description of studies that identified Ecel1 in sEVs
1
Experiment ID 15
MISEV standards
EM
Biophysical techniques
CD63
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors "Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO"
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Ecel1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Ece1  
Co-fractionation Mus musculus
2 Ece2  
Co-fractionation Mus musculus
3 Usp19  
Co-fractionation Mus musculus
View the network image/svg+xml
 Pathways in which Ecel1 is involved
No pathways found





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