Gene description for Amz2
Gene name archaelysin family metallopeptidase 2
Gene symbol Amz2
Other names/aliases AA408420
ESTM12
X83328
Species Mus musculus
 Database cross references - Amz2
ExoCarta ExoCarta_13929
Vesiclepedia VP_13929
Entrez Gene 13929
UniProt Q400C8  
 Amz2 identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Amz2
Molecular Function
    metallopeptidase activity GO:0008237 IEA
    metal ion binding GO:0046872 IEA
Biological Process
    proteolysis GO:0006508 IEA
Subcellular Localization
    cellular_component GO:0005575 ND
 Experiment description of studies that identified Amz2 in exosomes
1
Experiment ID 15
MISEV standards
EM
Biophysical techniques
CD63
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Amz2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Amz2 is involved
No pathways found





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here