Gene description for Chchd2
Gene name coiled-coil-helix-coiled-coil-helix domain containing 2
Gene symbol Chchd2
Other names/aliases AL033347
Etohi6
Species Mus musculus
 Database cross references - Chchd2
ExoCarta ExoCarta_14004
Entrez Gene 14004
UniProt Q9D1L0  
 Chchd2 identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Chchd2
Molecular Function
    sequence-specific DNA binding GO:0043565 ISO
    transcription factor binding GO:0008134 ISO
Biological Process
    positive regulation of transcription from RNA polymerase II promoter GO:0045944 ISO
    regulation of cellular response to hypoxia GO:1900037 ISO
Subcellular Localization
    mitochondrion GO:0005739 ISO
    nucleus GO:0005634 ISO
 Experiment description of studies that identified Chchd2 in exosomes
1
Experiment ID 15
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Chchd2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Chchd2 is involved
No pathways found





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