ExoCarta: Gene summary

Credits | Contact

Gene description for Echs1
Gene name	enoyl CoA hydratase, short chain, 1, mitochondrial
Gene symbol	Echs1
Other names/aliases	-
Species	Rattus norvegicus
Database cross references - Echs1
ExoCarta	ExoCarta_140547
Vesiclepedia	VP_140547
Entrez Gene	140547
UniProt	P14604
Echs1 identified in sEVs derived from the following tissue/cell type
Adipocytes	25998041

Gene ontology annotations for Echs1

Molecular Function
	delta(3)-delta(2)-enoyl-CoA isomerase activity	GO:0004165	IEA
	enoyl-CoA hydratase activity	GO:0004300	IDA
	enoyl-CoA hydratase activity	GO:0004300	IMP
	enoyl-CoA hydratase activity	GO:0004300	ISO
	hydro-lyase activity	GO:0016836	IEA
	3-hydroxypropionyl-CoA dehydratase activity	GO:0043956	ISO
	crotonyl-CoA hydratase activity	GO:0120092	IEA
Biological Process
	fatty acid beta-oxidation	GO:0006635	IBA
	fatty acid beta-oxidation	GO:0006635	IEA
	fatty acid beta-oxidation	GO:0006635	IMP
	fatty acid beta-oxidation	GO:0006635	ISO
	fatty acid beta-oxidation	GO:0006635	ISS
	fatty acid beta-oxidation	GO:0006635	TAS
Subcellular Localization
	mitochondrion	GO:0005739	IBA
	mitochondrion	GO:0005739	ISO
	mitochondrial matrix	GO:0005759	IEA

Experiment description of studies that identified Echs1 in sEVs

Experiment ID

225

MISEV standards
✔ EM	Biophysical techniques
✔ GAPDH\|CD63	Enriched markers
✘	Negative markers
✔ NTA	Particle analysis

Identified molecule

protein

Identification method

Mass spectrometry

PubMed ID

25998041

Organism

Rattus norvegicus

Experiment description

Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.

Authors

"Lee JE, Moon PG, Lee IK, Baek MC"

Journal name

Protein J

Publication year

2015

Sample

Adipocytes

Sample name

Adipocytes

Isolation/purification methods

Differential centrifugation
Filtration
Ultracentrifugation

Flotation density

Molecules identified in the study

Protein

Methods used in the study

Mass spectrometry
Western blotting

Protein-protein interactions for Echs1

	Protein Interactor	ExoCarta ID	Identification method	PubMed	Species
No interactions are found.

Pathways in which Echs1 is involved

Pathway	Evidence	Source
Beta oxidation of butanoyl-CoA to acetyl-CoA	IEA	Reactome
Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA	IEA	Reactome
Beta oxidation of hexanoyl-CoA to butanoyl-CoA	IEA	Reactome
Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA	IEA	Reactome
Beta oxidation of octanoyl-CoA to hexanoyl-CoA	IEA	Reactome
Branched-chain amino acid catabolism	IEA	Reactome
Fatty acid metabolism	IEA	Reactome
Metabolism	IEA	Reactome
Metabolism of amino acids and derivatives	IEA	Reactome
Metabolism of lipids	IEA	Reactome
Mitochondrial Fatty Acid Beta-Oxidation	IEA	Reactome
mitochondrial fatty acid beta-oxidation of saturated fatty acids	IEA	Reactome

Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here