Gene description for Sfxn1
Gene name sideroflexin 1
Gene symbol Sfxn1
Other names/aliases 2810002O05Rik
A930015P12Rik
f
Species Mus musculus
 Database cross references - Sfxn1
ExoCarta ExoCarta_14057
Entrez Gene 14057
UniProt Q99JR1  
 Sfxn1 identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Sfxn1
Molecular Function
    ion transmembrane transporter activity GO:0015075 IEA
    molecular_function GO:0003674 ND
Biological Process
    transmembrane transport GO:0055085 IEA
    transport GO:0006810 IEA
    erythrocyte differentiation GO:0030218 IMP
    ion transport GO:0006811 IEA
    iron ion transport GO:0006826 TAS
    iron ion homeostasis GO:0055072 IEA
Subcellular Localization
    membrane GO:0016020 IEA
    mitochondrion GO:0005739 ISO
    integral component of membrane GO:0016021 IEA
    mitochondrial inner membrane GO:0005743 IDA
 Experiment description of studies that identified Sfxn1 in exosomes
1
Experiment ID 15
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Sfxn1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Sfxn1 is involved
No pathways found





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