Gene description for F10
Gene name coagulation factor X
Gene symbol F10
Other names/aliases Cf10
fX
Species Mus musculus
 Database cross references - F10
ExoCarta ExoCarta_14058
Vesiclepedia VP_14058
Entrez Gene 14058
UniProt O88947  
 F10 identified in exosomes derived from the following tissue/cell type
Colon cancer cells 37309723    
T-cell lymphoma cells 37309723    
 Gene ontology annotations for F10
Molecular Function
    peptidase activity GO:0008233 IEA
    serine-type peptidase activity GO:0008236 IEA
    calcium ion binding GO:0005509 IEA
    hydrolase activity GO:0016787 IEA
    serine-type endopeptidase activity GO:0004252 ISO
    phospholipid binding GO:0005543 ISO
Biological Process
    proteolysis GO:0006508 ISO
    positive regulation of protein kinase B signaling GO:0051897 ISO
    hemostasis GO:0007599 IEA
    blood coagulation GO:0007596 ISO
Subcellular Localization
    intracellular membrane-bounded organelle GO:0043231 ISO
    membrane GO:0016020 ISO
    extracellular region GO:0005576 IEA
 Experiment description of studies that identified F10 in exosomes
1
Experiment ID 907
MISEV standards
EM
EV Biophysical techniques
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
EV Enriched markers
HSPA5
EV Negative markers
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S.
Journal name Proteomics
Publication year 2023
Sample Colon cancer cells
Sample name C26
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
2
Experiment ID 908
MISEV standards
EM
EV Biophysical techniques
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
EV Enriched markers
HSPA5
EV Negative markers
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S.
Journal name Proteomics
Publication year 2023
Sample T-cell lymphoma cells
Sample name EL4
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for F10
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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