Gene description for Rab3d
Gene name RAB3D, member RAS oncogene family
Gene symbol Rab3d
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Rab3d
ExoCarta ExoCarta_140665
Entrez Gene 140665
UniProt Q63942  
 Rab3d identified in exosomes derived from the following tissue/cell type
Hepatocytes 19367702    
 Gene ontology annotations for Rab3d
Molecular Function
    GTPase binding GO:0051020 IPI
    myosin V binding GO:0031489 ISO
    protein binding GO:0005515 IPI
    GTP binding GO:0005525 IEA
    GTPase activity GO:0003924 IBA
Biological Process
    regulation of exocytosis GO:0017157 ISO
    positive regulation of regulated secretory pathway GO:1903307 ISO
    protein localization to plasma membrane GO:0072659 IBA
    Rab protein signal transduction GO:0032482 IBA
    synaptic vesicle exocytosis GO:0016079 IBA
    protein secretion GO:0009306 IBA
    vesicle docking involved in exocytosis GO:0006904 IBA
    intracellular protein transport GO:0006886 IBA
    peptidyl-cysteine methylation GO:0018125 ISO
Subcellular Localization
    zymogen granule GO:0042588 ISO
    plasma membrane GO:0005886 IBA
    secretory granule membrane GO:0030667 IBA
    transport vesicle GO:0030133 IDA
    endosome GO:0005768 IBA
    synaptic vesicle GO:0008021 IBA
    extracellular exosome GO:0070062 ISO
    mitochondrion GO:0005739 ISO
 Experiment description of studies that identified Rab3d in exosomes
1
Experiment ID 35
ISEV standards
CEM
EV Biophysical techniques
TSG101|Alix
EV Cytosolic markers
CD81|CD63
EV Membrane markers
HSPA5
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19367702    
Organism Rattus norvegicus
Experiment description Characterization and Comprehensive Proteome Profiling of Exosomes Secreted by Hepatocytes.
Authors Conde-Vancells J, Rodriguez-Suarez E, Embade N, Gil D, Matthiesen R, Valle M, Elortza F, Lu SC, Mato JM, Falcon-Perez JM
Journal name JPR
Publication year 2008
Sample Hepatocytes
Sample name Hepatocytes
Isolation/purification methods Differential centrifugation
Filtration
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
Western blotting
 Protein-protein interactions for Rab3d
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Rab3d is involved
No pathways found





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