Gene description for Fabp5
Gene name fatty acid binding protein 5, epidermal
Gene symbol Fabp5
Other names/aliases C-FABP
DA11
E-FABP
Species Rattus norvegicus
 Database cross references - Fabp5
ExoCarta ExoCarta_140868
Vesiclepedia VP_140868
Entrez Gene 140868
UniProt P55053  
 Fabp5 identified in sEVs derived from the following tissue/cell type
Reticulocytes 21828046    
Reticulocytes 21828046    
Reticulocytes 21828046    
 Gene ontology annotations for Fabp5
Molecular Function
    retinoic acid binding GO:0001972 ISO
    long-chain fatty acid transmembrane transporter activity GO:0005324 ISO
    fatty acid binding GO:0005504 IBA
    fatty acid binding GO:0005504 IDA
    fatty acid binding GO:0005504 ISO
    lipid binding GO:0008289 IEA
    identical protein binding GO:0042802 ISO
Biological Process
    glucose metabolic process GO:0006006 ISO
    lipid metabolic process GO:0006629 ISO
    phosphatidylcholine biosynthetic process GO:0006656 ISO
    lipid transport GO:0006869 IEA
    negative regulation of D-glucose transmembrane transport GO:0010829 ISO
    fatty acid transport GO:0015908 IBA
    long-chain fatty acid transport GO:0015909 ISO
    regulation of prostaglandin biosynthetic process GO:0031392 ISO
    positive regulation of peroxisome proliferator activated receptor signaling pathway GO:0035360 ISO
    glucose homeostasis GO:0042593 ISO
    regulation of sensory perception of pain GO:0051930 ISO
    retrograde trans-synaptic signaling by endocannabinoid GO:0098921 ISO
    regulation of retrograde trans-synaptic signaling by endocanabinoid GO:0099178 ISO
    regulation of retrograde trans-synaptic signaling by endocanabinoid GO:0099178 ISS
    positive regulation of cold-induced thermogenesis GO:0120162 ISO
    positive regulation of cold-induced thermogenesis GO:0120162 ISS
    lipid transport across blood-brain barrier GO:1990379 ISO
Subcellular Localization
    extracellular region GO:0005576 IEA
    extracellular space GO:0005615 ISO
    extracellular space GO:0005615 ISS
    nucleus GO:0005634 IBA
    nucleus GO:0005634 IEA
    nucleus GO:0005634 ISO
    cytoplasm GO:0005737 IEA
    cytoplasm GO:0005737 ISO
    cytosol GO:0005829 IBA
    postsynaptic density GO:0014069 IEA
    postsynaptic density GO:0014069 ISO
    postsynaptic density GO:0014069 ISS
    synapse GO:0045202 ISO
    synapse GO:0045202 ISS
    glutamatergic synapse GO:0098978 ISO
    postsynaptic density, intracellular component GO:0099092 ISO
    postsynaptic cytosol GO:0099524 ISO
 Experiment description of studies that identified Fabp5 in sEVs
1
Experiment ID 96
MISEV standards
EM
Biophysical techniques
TSG101|HSP90|HSC70|MHCI
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors "Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E."
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D2 Rep 2
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.16-1.21 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
2
Experiment ID 97
MISEV standards
EM
Biophysical techniques
TSG101|HSP90|HSC70|MHCI
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors "Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E."
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D4 Rep 2
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.16-1.21 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
3
Experiment ID 98
MISEV standards
EM
Biophysical techniques
TSG101|HSP90|HSC70|MHCI
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors "Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E."
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D7 Rep 2
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.25 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
 Protein-protein interactions for Fabp5
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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