ExoCarta: Gene summary

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Gene description for Selenbp1
Gene name	selenium binding protein 1
Gene symbol	Selenbp1
Other names/aliases	Selenbp2
Species	Rattus norvegicus
Database cross references - Selenbp1
ExoCarta	ExoCarta_140927
Vesiclepedia	VP_140927
Entrez Gene	140927
UniProt	Q8VIF7
Selenbp1 identified in exosomes derived from the following tissue/cell type
Reticulocytes	21828046
Reticulocytes	21828046

Gene ontology annotations for Selenbp1

Molecular Function
	selenium binding	GO:0008430	IEA
Biological Process
	brown fat cell differentiation	GO:0050873	ISO
	protein transport	GO:0015031	IEA
Subcellular Localization
	cytosol	GO:0005829	IEA
	nucleus	GO:0005634	IEA
	extracellular exosome	GO:0070062	ISO
	membrane	GO:0016020	IEA
	extracellular space	GO:0005615	ISO
	nucleolus	GO:0005730	ISO

Experiment description of studies that identified Selenbp1 in exosomes

Experiment ID

MISEV standards
✔ EM	EV Biophysical techniques
✔ TSG101\|HSP90\|HSC70\|MHCI	EV Enriched markers
✘	EV Negative markers
✘	EV Particle analysis

Identified molecule

protein

Identification method

Mass spectrometry [Orbitrap]

PubMed ID

21828046

Organism

Rattus norvegicus

Experiment description

The proteo-lipidic composition of exosomes changes during reticulocyte maturation.

Authors

Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E.

Journal name

JBC

Publication year

2011

Sample

Reticulocytes

Sample name

Reticulocytes - D7 Rep 1

Isolation/purification methods

Differential centrifugation
Ultracentrifugation
Sucrose density gradient

Flotation density

1.13-1.25 g/mL

Molecules identified in the study

Protein
Lipids

Methods used in the study

Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting