Gene description for Fbp2
Gene name fructose bisphosphatase 2
Gene symbol Fbp2
Other names/aliases Fbp-1
Fbp1
Rae-30
Species Mus musculus
 Database cross references - Fbp2
ExoCarta ExoCarta_14120
Entrez Gene 14120
UniProt P70695  
 Fbp2 identified in exosomes derived from the following tissue/cell type
Pancreatic cells 19351151    
 Gene ontology annotations for Fbp2
Molecular Function
    catalytic activity GO:0003824 IEA
    hydrolase activity GO:0016787 IEA
    phosphoric ester hydrolase activity GO:0042578 IEA
    fructose 1,6-bisphosphate 1-phosphatase activity GO:0042132 ISO
    metal ion binding GO:0046872 IEA
Biological Process
    dephosphorylation GO:0016311 ISO
    metabolic process GO:0008152 IEA
    carbohydrate metabolic process GO:0005975 IEA
    gluconeogenesis GO:0006094 ISO
Subcellular Localization
    cell junction GO:0030054 IEA
    extracellular exosome GO:0070062 ISO
    nucleus GO:0005634 IEA
    cytoplasm GO:0005737 IEA
 Experiment description of studies that identified Fbp2 in exosomes
1
Experiment ID 188
ISEV standards
✔
EM
EV Biophysical techniques
✔
GAPDH|UCHL1|HSP90
EV Cytosolic markers
✘ EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19351151    
Organism Mus musculus
Experiment description Characterization of vesicles secreted from insulinoma NIT-1 cells.
Authors Lee HS, Jeong J, Lee KJ.
Journal name J Proteome Res
Publication year 2009
Sample Pancreatic cells
Sample name Pancreatic beta cell (NIT-1)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Fbp2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Fbp2 is involved
PathwayEvidenceSource
Gluconeogenesis IEA Reactome





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