Gene description for Fmod
Gene name fibromodulin
Gene symbol Fmod
Other names/aliases AI131919
AU041740
SLRR2E
Species Mus musculus
 Database cross references - Fmod
ExoCarta ExoCarta_14264
Entrez Gene 14264
UniProt P50608  
 Fmod identified in exosomes derived from the following tissue/cell type
Fibroblasts 23260141    
 Gene ontology annotations for Fmod
Subcellular Localization
    intracellular GO:0005622 ISO
    extracellular region GO:0005576 ISO
    extracellular space GO:0005615 ISO
    proteinaceous extracellular matrix GO:0005578 IEA
    extracellular matrix GO:0031012 ISO
 Experiment description of studies that identified Fmod in exosomes
1
Experiment ID 210
ISEV standards
✔
EM
EV Biophysical techniques
✘ EV Cytosolic markers
✔
CD81|FLOT1
EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23260141    
Organism Mus musculus
Experiment description Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration.
Authors Luga V, Zhang L, Viloria-Petit AM, Ogunjimi AA, Inanlou MR, Chiu E, Buchanan M, Hosein AN, Basik M, Wrana JL.
Journal name Cell
Publication year 2012
Sample Fibroblasts
Sample name Normal-Fibroblasts (L cells)
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Fmod
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Fmod is involved
PathwayEvidenceSource
ECM proteoglycans IEA Reactome
Keratan sulfate biosynthesis IEA Reactome
Keratan sulfate degradation IEA Reactome





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