Gene description for Gh
Gene name growth hormone
Gene symbol Gh
Other names/aliases Gh1
Species Mus musculus
 Database cross references - Gh
ExoCarta ExoCarta_14599
Entrez Gene 14599
UniProt P06880  
 Gh identified in exosomes derived from the following tissue/cell type
Pancreatic cells 19351151    
 Gene ontology annotations for Gh
Molecular Function
    metal ion binding GO:0046872 IEA
    hormone activity GO:0005179 ISO
    growth hormone receptor binding GO:0005131 ISO
Biological Process
    regulation of intracellular steroid hormone receptor signaling pathway GO:0033143 ISO
    glucose transport GO:0015758 ISO
    lung alveolus development GO:0048286 ISO
    negative regulation of neuron death GO:1901215 ISO
    response to light stimulus GO:0009416 ISO
    positive regulation of neurogenesis GO:0050769 ISO
    neuroblast proliferation GO:0007405 ISO
    positive regulation of steroid hormone biosynthetic process GO:0090031 ISO
    response to food GO:0032094 IDA
    cellular response to insulin stimulus GO:0032869 IDA
    positive regulation of multicellular organism growth GO:0040018 IGI
    positive regulation of growth GO:0045927 ISO
Subcellular Localization
    trans-Golgi network GO:0005802 IDA
    plasma membrane GO:0005886 IDA
    secretory granule GO:0030141 ISO
    extracellular space GO:0005615 ISO
    extracellular region GO:0005576 IEA
    nucleus GO:0005634 ISO
    cytosol GO:0005829 ISO
    mitochondrion GO:0005739 ISO
 Experiment description of studies that identified Gh in exosomes
1
Experiment ID 188
ISEV standards
EM
EV Biophysical techniques
GAPDH|UCHL1|HSP90
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19351151    
Organism Mus musculus
Experiment description Characterization of vesicles secreted from insulinoma NIT-1 cells.
Authors Lee HS, Jeong J, Lee KJ.
Journal name J Proteome Res
Publication year 2009
Sample Pancreatic cells
Sample name Pancreatic beta cell (NIT-1)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Gh
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here