Gene description for Galk1
Gene name galactokinase 1
Gene symbol Galk1
Other names/aliases AA409894
GALK
Gk
Glk
Glk1
Species Mus musculus
 Database cross references - Galk1
ExoCarta ExoCarta_14635
Entrez Gene 14635
UniProt Q9R0N0  
 Galk1 identified in exosomes derived from the following tissue/cell type
Fibroblasts 23260141    
 Gene ontology annotations for Galk1
Molecular Function
    ATP binding GO:0005524 ISO
    transferase activity GO:0016740 IEA
    phosphotransferase activity, alcohol group as acceptor GO:0016773 IEA
    nucleotide binding GO:0000166 IEA
    galactokinase activity GO:0004335 ISO
    galactose binding GO:0005534 ISO
    protein binding GO:0005515 IPI
    kinase activity GO:0016301 IEA
Biological Process
    carbohydrate metabolic process GO:0005975 IEA
    phosphorylation GO:0016310 IEA
    metabolic process GO:0008152 IEA
    galactose metabolic process GO:0006012 ISO
    galactitol metabolic process GO:0019402 IMP
    carbohydrate phosphorylation GO:0046835 ISO
Subcellular Localization
    extracellular exosome GO:0070062 ISO
    cytoplasm GO:0005737 ISO
 Experiment description of studies that identified Galk1 in exosomes
1
Experiment ID 210
ISEV standards
✔
EM
EV Biophysical techniques
✘ EV Cytosolic markers
✔
CD81|FLOT1
EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23260141    
Organism Mus musculus
Experiment description Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration.
Authors Luga V, Zhang L, Viloria-Petit AM, Ogunjimi AA, Inanlou MR, Chiu E, Buchanan M, Hosein AN, Basik M, Wrana JL.
Journal name Cell
Publication year 2012
Sample Fibroblasts
Sample name Normal-Fibroblasts (L cells)
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Galk1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Galk1 is involved
PathwayEvidenceSource
Galactose catabolism IEA Reactome





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here