Gene description for Hbb-y
Gene name hemoglobin Y, beta-like embryonic chain
Gene symbol Hbb-y
Other names/aliases Ey
Hby
Species Mus musculus
 Database cross references - Hbb-y
ExoCarta ExoCarta_15135
Vesiclepedia VP_15135
Entrez Gene 15135
UniProt P02104  
 Hbb-y identified in sEVs derived from the following tissue/cell type
Mov neuroglial cells 15210972    
 Gene ontology annotations for Hbb-y
Molecular Function
    peroxidase activity GO:0004601 IBA
    oxygen carrier activity GO:0005344 IBA
    oxygen carrier activity GO:0005344 IEA
    oxygen carrier activity GO:0005344 ISO
    oxygen binding GO:0019825 IBA
    oxygen binding GO:0019825 IEA
    heme binding GO:0020037 IBA
    heme binding GO:0020037 IEA
    haptoglobin binding GO:0031720 IBA
    hemoglobin alpha binding GO:0031721 IBA
    hemoglobin alpha binding GO:0031721 ISO
    protein-containing complex binding GO:0044877 ISO
    metal ion binding GO:0046872 IEA
Biological Process
    negative regulation of transcription by RNA polymerase II GO:0000122 IGI
    negative regulation of transcription by RNA polymerase II GO:0000122 IMP
    carbon dioxide transport GO:0015670 NAS
    oxygen transport GO:0015671 NAS
    hydrogen peroxide catabolic process GO:0042744 IBA
Subcellular Localization
    hemoglobin complex GO:0005833 IBA
    hemoglobin complex GO:0005833 ISO
    hemoglobin complex GO:0005833 NAS
    haptoglobin-hemoglobin complex GO:0031838 IBA
 Experiment description of studies that identified Hbb-y in sEVs
1
Experiment ID 39
MISEV standards
IEM
Biophysical techniques
TSG101|HSC70|FLOT1
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 15210972    
Organism Mus musculus
Experiment description Cells release prions in association with exosomes.
Authors "Fevrier B, Vilette D, Archer F, Loew D, Faigle W, Vidal M, Laude H, Raposo G"
Journal name PNAS
Publication year 2004
Sample Mov neuroglial cells
Sample name Mov neuroglial cell
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.14 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QSTAR]
Western blotting
Immunoelectron Microscopy
 Protein-protein interactions for Hbb-y
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Eed  
Affinity Capture-MS Mus musculus
View the network image/svg+xml
 Pathways in which Hbb-y is involved
No pathways found





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