Gene description for Hbb-y
Gene name hemoglobin Y, beta-like embryonic chain
Gene symbol Hbb-y
Other names/aliases Ey
Species Mus musculus
 Database cross references - Hbb-y
ExoCarta ExoCarta_15135
Entrez Gene 15135
UniProt P02104  
 Hbb-y identified in exosomes derived from the following tissue/cell type
Mov neuroglial cells 15210972    
 Gene ontology annotations for Hbb-y
Molecular Function
    iron ion binding GO:0005506 IEA
    oxygen transporter activity GO:0005344 IEA
    metal ion binding GO:0046872 IEA
    hemoglobin alpha binding GO:0031721 ISO
    oxygen binding GO:0019825 IEA
    heme binding GO:0020037 IEA
Biological Process
    transport GO:0006810 IEA
    protein heterooligomerization GO:0051291 ISO
    oxygen transport GO:0015671 IEA
    negative regulation of transcription from RNA polymerase II promoter GO:0000122 IMP
Subcellular Localization
    hemoglobin complex GO:0005833 ISO
    blood microparticle GO:0072562 ISO
 Experiment description of studies that identified Hbb-y in exosomes
Experiment ID 39
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 15210972    
Organism Mus musculus
Experiment description Cells release prions in association with exosomes.
Authors Fevrier B, Vilette D, Archer F, Loew D, Faigle W, Vidal M, Laude H, Raposo G
Journal name PNAS
Publication year 2004
Sample Mov neuroglial cells
Sample name Mov neuroglial cell
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.14 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QSTAR]
Western blotting
Immunoelectron Microscopy
 Protein-protein interactions for Hbb-y
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Hbb-y is involved
No pathways found

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