Gene description for Hmgb1
Gene name	high mobility group box 1
Gene symbol	Hmgb1
Other names/aliases	DEF HMG-1 Hmg1 SBP-1 amphoterin p30
Species	Mus musculus
Database cross references - Hmgb1
ExoCarta	ExoCarta_15289
Entrez Gene	15289
UniProt	P63158
Hmgb1 identified in exosomes derived from the following tissue/cell type
Mast cells	17486113
Pancreatic cells	19351151

Gene ontology annotations for Hmgb1

Molecular Function     protein kinase activator activity GO:0030295 IDA     chromatin binding GO:0003682 IBA     bent DNA binding GO:0003681 ISO     open form four-way junction DNA binding GO:0000401 ISO     crossed form four-way junction DNA binding GO:0000402 ISO     cytokine activity GO:0005125 ISO     calcium-dependent protein kinase regulator activity GO:0010858 IDA Biological Process     eye development GO:0001654 IMP     positive regulation of mitotic cell cycle GO:0045931 ISO     positive regulation of protein kinase activity GO:0045860 IDA     DNA geometric change GO:0032392 ISO     response to glucocorticoid GO:0051384 IMP     positive regulation of transcription from RNA polymerase II promoter GO:0045944 IMP     induction of positive chemotaxis GO:0050930 ISO     lung development GO:0030324 IMP     positive regulation of cell migration GO:0030335 ISO     positive regulation of mesenchymal cell proliferation GO:0002053 ISO     chromatin remodeling GO:0006338 IBA     positive regulation of myeloid cell differentiation GO:0045639 IDA     positive regulation of protein phosphorylation GO:0001934 IDA     positive regulation of glycogen catabolic process GO:0045819 IMP Subcellular Localization     nucleus GO:0005634 IDA     extracellular space GO:0005615 IDA     cytoplasm GO:0005737 IDA     neuron projection GO:0043005 IDA