Gene description for Hmgn1
Gene name high mobility group nucleosomal binding domain 1
Gene symbol Hmgn1
Other names/aliases HMG-14
Hmg14
Species Mus musculus
 Database cross references - Hmgn1
ExoCarta ExoCarta_15312
Vesiclepedia VP_15312
Entrez Gene 15312
UniProt P18608  
 Hmgn1 identified in sEVs derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Hmgn1
Molecular Function
    chromatin binding GO:0003682 IBA
    chromatin binding GO:0003682 IDA
    protein binding GO:0005515 IPI
    nucleosomal DNA binding GO:0031492 IEA
Biological Process
    pyrimidine dimer repair by nucleotide-excision repair GO:0000720 IMP
    transcription-coupled nucleotide-excision repair GO:0006283 IMP
    chromatin organization GO:0006325 IBA
    chromatin organization GO:0006325 IMP
    regulation of transcription by RNA polymerase II GO:0006357 IMP
    response to UV-B GO:0010224 IMP
    response to UV-C GO:0010225 IDA
    regulation of development, heterochronic GO:0040034 IGI
    post-embryonic camera-type eye morphogenesis GO:0048597 IMP
    regulation of epithelial cell proliferation GO:0050678 IMP
    positive regulation of NAD+ ADP-ribosyltransferase activity GO:1901666 IMP
Subcellular Localization
    chromatin GO:0000785 IEA
    female germ cell nucleus GO:0001674 IDA
    nucleus GO:0005634 IBA
    nucleus GO:0005634 IDA
    nucleoplasm GO:0005654 IEA
    nucleoplasm GO:0005654 ISO
    cytoplasm GO:0005737 IEA
 Experiment description of studies that identified Hmgn1 in sEVs
1
Experiment ID 15
MISEV standards
EM
Biophysical techniques
CD63
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors "Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO"
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Hmgn1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 JADE1  
Affinity Capture-MS Homo sapiens
2 Atg16l1  
Affinity Capture-MS Mus musculus
View the network image/svg+xml
 Pathways in which Hmgn1 is involved
No pathways found





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