Gene description for Hmox1
Gene name	heme oxygenase 1
Gene symbol	Hmox1
Other names/aliases	D8Wsu38e HO-1 HO1 Hemox Hmox Hsp32
Species	Mus musculus
Database cross references - Hmox1
ExoCarta	ExoCarta_15368
Entrez Gene	15368
UniProt	P14901
Hmox1 identified in exosomes derived from the following tissue/cell type
Pancreatic cells	19351151

Gene ontology annotations for Hmox1

Molecular Function     enzyme binding GO:0019899 ISO     phospholipase D activity GO:0004630 ISO     heme binding GO:0020037 ISO     protein homodimerization activity GO:0042803 ISO     heme oxygenase (decyclizing) activity GO:0004392 ISO     signal transducer activity GO:0004871 ISO     metal ion binding GO:0046872 IEA     oxidoreductase activity GO:0016491 ISO Biological Process     negative regulation of neuron apoptotic process GO:0043524 ISO     heme metabolic process GO:0042168 IDA     negative regulation of muscle cell apoptotic process GO:0010656 ISO     regulation of transcription from RNA polymerase II promoter in response to oxidative stress GO:0043619 ISO     wound healing involved in inflammatory response GO:0002246 ISO     regulation of sequence-specific DNA binding transcription factor activity GO:0051090 ISO     negative regulation of DNA binding GO:0043392 ISO     intrinsic apoptotic signaling pathway in response to DNA damage GO:0008630 ISO     response to estrogen GO:0043627 ISO     positive regulation of smooth muscle cell proliferation GO:0048661 ISO     heme catabolic process GO:0042167 ISO     response to hydrogen peroxide GO:0042542 ISO     apoptotic process GO:0006915 IEA     erythrocyte homeostasis GO:0034101 ISO     cellular response to arsenic-containing substance GO:0071243 IDA     cellular response to cadmium ion GO:0071276 IDA     negative regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902042 ISO     positive regulation of I-kappaB kinase/NF-kappaB signaling GO:0043123 ISO     response to nicotine GO:0035094 ISO     cellular iron ion homeostasis GO:0006879 ISO     iron ion homeostasis GO:0055072 ISO     regulation of transcription from RNA polymerase II promoter in response to iron GO:0034395 IDA     negative regulation of sequence-specific DNA binding transcription factor activity GO:0043433 ISO     heme oxidation GO:0006788 ISO     negative regulation of mast cell degranulation GO:0043305 ISO     negative regulation of mast cell cytokine production GO:0032764 ISO     oxidation-reduction process GO:0055114 IEA     response to oxidative stress GO:0006979 ISO     negative regulation of smooth muscle cell proliferation GO:0048662 ISO     cell death GO:0008219 ISO     protein homooligomerization GO:0051260 ISO     intracellular signal transduction GO:0035556 ISO     positive regulation of angiogenesis GO:0045766 ISO     negative regulation of cell proliferation GO:0008285 ISO     cellular response to heat GO:0034605 ISO     angiogenesis GO:0001525 ISO     small GTPase mediated signal transduction GO:0007264 ISO     regulation of blood pressure GO:0008217 ISO Subcellular Localization     caveola GO:0005901 ISO     endoplasmic reticulum GO:0005783 ISO     membrane GO:0016020 IEA     intracellular membrane-bounded organelle GO:0043231 IEA     perinuclear region of cytoplasm GO:0048471 ISO     nucleolus GO:0005730 ISO     nucleus GO:0005634 ISO     cytosol GO:0005829 ISO