Gene description for Icam1
Gene name	intercellular adhesion molecule 1
Gene symbol	Icam1
Other names/aliases	CD54 Icam-1 Ly-47 MALA-2
Species	Mus musculus
Database cross references - Icam1
ExoCarta	ExoCarta_15894
Entrez Gene	15894
UniProt	P13597
Icam1 identified in exosomes derived from the following tissue/cell type
Macrophages	23658846
Macrophages	23658846
Macrophages	23658846
Mast cells	11145662
Mast cells	11306949
Mast cells	17486113

Gene ontology annotations for Icam1

Molecular Function     integrin binding GO:0005178 ISO     protein complex binding GO:0032403 ISO Biological Process     positive regulation of vasoconstriction GO:0045907 ISO     receptor-mediated virion attachment to host cell GO:0046813 ISO     positive regulation of nitric oxide biosynthetic process GO:0045429 ISO     regulation of ruffle assembly GO:1900027 IDA     positive regulation of cellular extravasation GO:0002693 ISO     regulation of cell adhesion GO:0030155 IDA     sensory perception of sound GO:0007605 ISO     adhesion of symbiont to host GO:0044406 ISO     negative regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902042 ISO     positive regulation of NF-kappaB transcription factor activity GO:0051092 ISO     positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 ISO     cell adhesion mediated by integrin GO:0033627 IDA     single organismal cell-cell adhesion GO:0016337 ISO     regulation of cell shape GO:0008360 ISO     positive regulation of GTPase activity GO:0043547 ISO     negative regulation of endothelial cell apoptotic process GO:2000352 ISO     establishment of endothelial barrier GO:0061028 ISO     positive regulation of actin filament polymerization GO:0030838 ISO     cell adhesion GO:0007155 ISO     negative regulation of calcium ion transport GO:0051926 ISO     cellular response to glucose stimulus GO:0071333 IDA     leukocyte cell-cell adhesion GO:0007159 ISO     positive regulation of ERK1 and ERK2 cascade GO:0070374 ISO     establishment of Sertoli cell barrier GO:0097368 ISO     acute inflammatory response to antigenic stimulus GO:0002438 ISO     T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell GO:0002291 ISO     T cell antigen processing and presentation GO:0002457 IDA Subcellular Localization     extracellular space GO:0005615 ISO     membrane GO:0016020 ISO     extracellular exosome GO:0070062 ISO     integral component of membrane GO:0016021 IEA     cell surface GO:0009986 ISO     membrane raft GO:0045121 IDA     integral component of plasma membrane GO:0005887 IBA     focal adhesion GO:0005925 ISO     plasma membrane GO:0005886 ISO     immunological synapse GO:0001772 IDA     external side of plasma membrane GO:0009897 IDA