Gene description for Jchain |
Gene name |
immunoglobulin joining chain |
Gene symbol |
Jchain |
Other names/aliases |
9530090F24Rik AI323815 Igj Jch |
Species |
Mus musculus |
Database cross references - Jchain |
ExoCarta |
ExoCarta_16069 |
Vesiclepedia |
VP_16069 |
Entrez Gene |
16069 |
UniProt |
P01592
|
Jchain identified in sEVs derived from the following tissue/cell type |
Faeces
|
33431899
|
Faeces
|
33431899
|
Gene ontology annotations for Jchain |
|
Experiment description of studies that identified Jchain in sEVs |
1 |
Experiment ID |
303 |
MISEV standards |
✔
EM
|
Biophysical techniques |
✔
Cd63|Cd81|Cd9
|
Enriched markers |
✘
|
Negative markers |
✔
NTA
|
Particle analysis
|
|
Identified molecule |
Protein
|
Identification method |
Mass spectrometry
|
PubMed ID |
33431899
|
Organism |
Mus musculus |
Experiment description |
High-fat diet-induced upregulation of exosomal phosphatidylcholine contributes to insulin resistance |
Authors |
"Kumar A, Sundaram K, Mu J, Dryden GW, Sriwastva MK, Lei C, Zhang L, Qiu X, Xu F, Yan J, Zhang X, Park JW, Merchant ML, Bohler HCL, Wang B, Zhang S, Qin C, Xu Z, Han X, McClain CJ, Teng Y, Zhang HG." |
Journal name |
Nat Commun
|
Publication year |
2021 |
Sample |
Faeces |
Sample name |
Intestinal epithelial cells - C57BL/6 |
Isolation/purification methods |
Differential centrifugation Ultracentrifugation Sucrose density gradient centrifugation |
Flotation density |
-
|
Molecules identified in the study |
Protein Lipid miRNA |
Methods used in the study |
Western blotting Mass spectrometry Immunofluorescence miRNA array HPLC |
|
|
2 |
Experiment ID |
304 |
MISEV standards |
✔
EM
|
Biophysical techniques |
✔
Cd63|Cd81|Cd9
|
Enriched markers |
✘
|
Negative markers |
✔
NTA
|
Particle analysis
|
|
Identified molecule |
Protein
|
Identification method |
Mass spectrometry
|
PubMed ID |
33431899
|
Organism |
Mus musculus |
Experiment description |
High-fat diet-induced upregulation of exosomal phosphatidylcholine contributes to insulin resistance |
Authors |
"Kumar A, Sundaram K, Mu J, Dryden GW, Sriwastva MK, Lei C, Zhang L, Qiu X, Xu F, Yan J, Zhang X, Park JW, Merchant ML, Bohler HCL, Wang B, Zhang S, Qin C, Xu Z, Han X, McClain CJ, Teng Y, Zhang HG." |
Journal name |
Nat Commun
|
Publication year |
2021 |
Sample |
Faeces |
Sample name |
Intestinal epithelial cells - C57BL/6 |
Isolation/purification methods |
Differential centrifugation Ultracentrifugation Sucrose density gradient centrifugation |
Flotation density |
-
|
Molecules identified in the study |
Protein Lipid miRNA |
Methods used in the study |
Western blotting Mass spectrometry Immunofluorescence miRNA array HPLC |
|
|
Protein-protein interactions for Jchain |
|
Pathways in which Jchain is involved |
|
|
|