Gene description for Itga7
Gene name integrin alpha 7
Gene symbol Itga7
Other names/aliases [a]7
Species Mus musculus
 Database cross references - Itga7
ExoCarta ExoCarta_16404
Entrez Gene 16404
 Itga7 identified in exosomes derived from the following tissue/cell type
Mov neuroglial cells 15210972    
 Gene ontology annotations for Itga7
Molecular Function
    protein heterodimerization activity GO:0046982 ISO
    metal ion binding GO:0046872 IEA
    integrin binding GO:0005178 ISO
    laminin binding GO:0043236 ISO
    protein binding GO:0005515 IPI
    cell adhesion molecule binding GO:0050839 ISO
Biological Process
    cell adhesion GO:0007155 ISO
    integrin-mediated signaling pathway GO:0007229 ISO
    regulation of cell shape GO:0008360 IEA
    blood vessel morphogenesis GO:0048514 IMP
    cell migration GO:0016477 IMP
    heterotypic cell-cell adhesion GO:0034113 ISO
Subcellular Localization
    integrin complex GO:0008305 ISO
    neuromuscular junction GO:0031594 IDA
    muscle tendon junction GO:0005927 IDA
    cell surface GO:0009986 ISO
    cytoplasm GO:0005737 IDA
    membrane GO:0016020 IEA
    integral component of membrane GO:0016021 IEA
    sarcolemma GO:0042383 IDA
    integrin alpha7-beta1 complex GO:0034677 IPI
 Experiment description of studies that identified Itga7 in exosomes
Experiment ID 39
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 15210972    
Organism Mus musculus
Experiment description Cells release prions in association with exosomes.
Authors Fevrier B, Vilette D, Archer F, Loew D, Faigle W, Vidal M, Laude H, Raposo G
Journal name PNAS
Publication year 2004
Sample Mov neuroglial cells
Sample name Mov neuroglial cell
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.14 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QSTAR]
Western blotting
Immunoelectron Microscopy
 Protein-protein interactions for Itga7
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Itga7 is involved
No pathways found

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