Gene description for Jund
Gene name jun D proto-oncogene
Gene symbol Jund
Other names/aliases Jund1
Species Mus musculus
 Database cross references - Jund
ExoCarta ExoCarta_16478
Entrez Gene 16478
UniProt P15066  
 Jund identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Jund
Molecular Function
    protein binding GO:0005515 IPI
    DNA binding GO:0003677 IDA
    RNA polymerase II core promoter proximal region sequence-specific DNA binding GO:0000978 IDA
    double-stranded DNA binding GO:0003690 ISO
    sequence-specific DNA binding transcription factor activity GO:0003700 ISO
    sequence-specific DNA binding RNA polymerase II transcription factor activity GO:0000981 IBA
    transcription factor binding GO:0008134 IPI
    enzyme binding GO:0019899 ISO
    ligand-dependent nuclear receptor binding GO:0016922 ISO
    sequence-specific DNA binding GO:0043565 ISO
    transcription regulatory region DNA binding GO:0044212 ISO
    transcription coactivator activity GO:0003713 IBA
Biological Process
    transcription from RNA polymerase II promoter GO:0006366 ISO
    positive regulation of osteoblast differentiation GO:0045669 IGI
    response to lipopolysaccharide GO:0032496 IBA
    osteoblast development GO:0002076 IGI
    positive regulation of transcription from RNA polymerase II promoter GO:0045944 IGI
    response to cAMP GO:0051591 IBA
    cellular response to hormone stimulus GO:0032870 IBA
    regulation of cell cycle GO:0051726 IBA
    transcription, DNA-templated GO:0006351 IEA
    negative regulation of transcription from RNA polymerase II promoter GO:0000122 IBA
    regulation of transcription, DNA-templated GO:0006355 ISO
    response to cytokine GO:0034097 IBA
    cellular response to calcium ion GO:0071277 IDA
    response to drug GO:0042493 IBA
    response to mechanical stimulus GO:0009612 IBA
    regulation of cell proliferation GO:0042127 IBA
    regulation of cell death GO:0010941 IBA
    response to radiation GO:0009314 IBA
    regulation of transcription from RNA polymerase II promoter GO:0006357 IEA
Subcellular Localization
    nucleus GO:0005634 ISO
    protein complex GO:0043234 ISO
    transcription factor complex GO:0005667 IBA
    protein-DNA complex GO:0032993 ISO
    nuclear chromatin GO:0000790 IBA
    nucleoplasm GO:0005654 ISO
 Experiment description of studies that identified Jund in exosomes
1
Experiment ID 15
ISEV standards
✔
EM
EV Biophysical techniques
✘ EV Cytosolic markers
✔
CD63
EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Jund
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Jund is involved
No pathways found





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