Gene description for Kcnj11
Gene name	potassium inwardly rectifying channel, subfamily J, member 11
Gene symbol	Kcnj11
Other names/aliases	Kir6.2 mBIR
Species	Mus musculus
Database cross references - Kcnj11
ExoCarta	ExoCarta_16514
Vesiclepedia	VP_16514
Entrez Gene	16514
UniProt	Q61743
Kcnj11 identified in sEVs derived from the following tissue/cell type
Mast cells	17486113

Gene ontology annotations for Kcnj11

Molecular Function     inward rectifier potassium channel activity GO:0005242 IDA     inward rectifier potassium channel activity GO:0005242 IMP     voltage-gated potassium channel activity GO:0005249 ISO     protein binding GO:0005515 IPI     ATP binding GO:0005524 IDA     ATP-activated inward rectifier potassium channel activity GO:0015272 IBA     ATP-activated inward rectifier potassium channel activity GO:0015272 IDA     ATP-activated inward rectifier potassium channel activity GO:0015272 ISO     ATPase-coupled monoatomic cation transmembrane transporter activity GO:0019829 IEA     ATPase-coupled monoatomic cation transmembrane transporter activity GO:0019829 ISO     ankyrin binding GO:0030506 IPI     ankyrin binding GO:0030506 ISO     potassium ion binding GO:0030955 IC     heat shock protein binding GO:0031072 IEA     heat shock protein binding GO:0031072 ISO     transmembrane transporter binding GO:0044325 IEA     transmembrane transporter binding GO:0044325 ISO     voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential GO:0099508 IEA     voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential GO:0099508 ISO Biological Process     action potential GO:0001508 IGI     action potential GO:0001508 IMP     response to hypoxia GO:0001666 IMP     response to ischemia GO:0002931 IMP     ventricular cardiac muscle tissue development GO:0003229 IGI     glucose metabolic process GO:0006006 IEA     glucose metabolic process GO:0006006 ISO     potassium ion transport GO:0006813 ISO     apoptotic process GO:0006915 IMP     response to stress GO:0006950 IGI     determination of adult lifespan GO:0008340 IGI     response to xenobiotic stimulus GO:0009410 IEA     response to xenobiotic stimulus GO:0009410 ISO     cellular response to nutrient levels GO:0031669 IMP     response to estradiol GO:0032355 IEA     response to ATP GO:0033198 IEA     response to ATP GO:0033198 ISO     response to testosterone GO:0033574 IEA     regulation of monoatomic ion transmembrane transport GO:0034765 IBA     regulation of membrane potential GO:0042391 ISO     negative regulation of insulin secretion GO:0046676 IMP     negative regulation of insulin secretion GO:0046676 ISO     regulation of insulin secretion GO:0050796 ISO     nervous system process GO:0050877 IEA     nervous system process GO:0050877 ISO     CAMKK-AMPK signaling cascade GO:0061762 IMP     cellular response to nicotine GO:0071316 IEA     cellular response to glucose stimulus GO:0071333 IEA     cellular response to tumor necrosis factor GO:0071356 IEA     potassium ion transmembrane transport GO:0071805 ISO     inorganic cation transmembrane transport GO:0098662 ISO     regulation of presynaptic membrane potential GO:0099505 IEA     positive regulation of protein localization to plasma membrane GO:1903078 IEA     positive regulation of protein localization to plasma membrane GO:1903078 ISO     response to resveratrol GO:1904638 IMP     potassium ion import across plasma membrane GO:1990573 IBA     potassium ion import across plasma membrane GO:1990573 IDA     potassium ion import across plasma membrane GO:1990573 ISO     potassium ion import across plasma membrane GO:1990573 ISS Subcellular Localization     acrosomal vesicle GO:0001669 IEA     acrosomal vesicle GO:0001669 ISO     nuclear envelope GO:0005635 IEA     nuclear envelope GO:0005635 ISO     cytoplasm GO:0005737 IDA     endosome GO:0005768 IEA     endosome GO:0005768 ISO     plasma membrane GO:0005886 IBA     plasma membrane GO:0005886 IDA     plasma membrane GO:0005886 IDA     plasma membrane GO:0005886 ISO     inward rectifying potassium channel GO:0008282 IDA     inward rectifying potassium channel GO:0008282 ISO     inward rectifying potassium channel GO:0008282 ISS     intercalated disc GO:0014704 IEA     intercalated disc GO:0014704 ISO     T-tubule GO:0030315 IDA     T-tubule GO:0030315 ISO     axolemma GO:0030673 IEA     axolemma GO:0030673 ISO     sarcolemma GO:0042383 ISO     presynaptic membrane GO:0042734 IEA     presynaptic membrane GO:0042734 ISO     neuronal cell body GO:0043025 IEA     neuronal cell body GO:0043025 ISO     cell body fiber GO:0070852 IEA     cell body fiber GO:0070852 ISO     glutamatergic synapse GO:0098978 IEA     glutamatergic synapse GO:0098978 ISO