Gene description for Kcnj15
Gene name potassium inwardly-rectifying channel, subfamily J, member 15
Gene symbol Kcnj15
Other names/aliases 4930414N08Rik
AI182284
AI267127
IRKK
Kir4.2
Species Mus musculus
 Database cross references - Kcnj15
ExoCarta ExoCarta_16516
Entrez Gene 16516
UniProt O88932  
 Kcnj15 identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Kcnj15
Molecular Function
    protein binding GO:0005515 IPI
    potassium channel activity GO:0005267 IDA
    inward rectifier potassium channel activity GO:0005242 ISO
    voltage-gated ion channel activity GO:0005244 IEA
Biological Process
    potassium ion import GO:0010107 IBA
    potassium ion transport GO:0006813 IDA
    potassium ion transmembrane transport GO:0071805 IDA
    ion transport GO:0006811 IEA
    transport GO:0006810 IEA
    regulation of ion transmembrane transport GO:0034765 ISO
Subcellular Localization
    integral component of plasma membrane GO:0005887 IBA
    integral component of membrane GO:0016021 IC
    plasma membrane GO:0005886 ISO
    membrane GO:0016020 IEA
 Experiment description of studies that identified Kcnj15 in exosomes
1
Experiment ID 15
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Kcnj15
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Inadl  
Two-hybrid Mus musculus
Reconstituted Complex Mus musculus
View the network image/svg+xml



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