Gene description for Kcnj3
Gene name potassium inwardly-rectifying channel, subfamily J, member 3
Gene symbol Kcnj3
Other names/aliases GIRK-1
GIRK1
Kcnf3
Kir3.1
Species Mus musculus
 Database cross references - Kcnj3
ExoCarta ExoCarta_16519
Entrez Gene 16519
UniProt P63250  
 Kcnj3 identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Kcnj3
Molecular Function
    G-protein activated inward rectifier potassium channel activity GO:0015467 TAS
    voltage-gated ion channel activity GO:0005244 IEA
    inward rectifier potassium channel activity GO:0005242 ISO
Biological Process
    potassium ion import GO:0010107 IBA
    ion transport GO:0006811 IEA
    regulation of ion transmembrane transport GO:0034765 TAS
    transport GO:0006810 IEA
    potassium ion transport GO:0006813 IEA
    potassium ion transmembrane transport GO:0071805 TAS
Subcellular Localization
    integral component of plasma membrane GO:0005887 IBA
    membrane GO:0016020 IEA
    integral component of membrane GO:0016021 IEA
    cell surface GO:0009986 ISO
    T-tubule GO:0030315 ISO
    external side of plasma membrane GO:0009897 ISO
 Experiment description of studies that identified Kcnj3 in exosomes
1
Experiment ID 15
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Kcnj3
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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