Gene description for Fabp5 |
Gene name |
fatty acid binding protein 5, epidermal |
Gene symbol |
Fabp5 |
Other names/aliases |
E-FABP Fabpe Klbp PA-FABP mal1 |
Species |
Mus musculus |
Database cross references - Fabp5 |
ExoCarta |
ExoCarta_16592 |
Entrez Gene |
16592 |
UniProt |
Q05816
|
Fabp5 identified in exosomes derived from the following tissue/cell type |
Basophilic leukemia cells
|
20424270
|
Mast cells
|
17486113
|
Neural stem cells
|
25242146
|
Oligodendrocytes
|
21136642
|
Gene ontology annotations for Fabp5 |
|
Experiment description of studies that identified Fabp5 in exosomes |
1 |
Experiment ID |
89 |
ISEV standards |
✔
EM
|
EV Biophysical techniques |
✘
|
EV Cytosolic markers |
✘
|
EV Membrane markers |
✘
|
EV Negative markers |
✔
DLS
|
EV Particle analysis
|
|
Identified molecule |
protein
|
Identification method |
Mass spectrometry
|
PubMed ID |
20424270
|
Organism |
Rattus norvegicus |
Experiment description |
Exosomes account for vesicle-mediated transcellular transport of activatable phospholipases and prostaglandins. |
Authors |
Subra C, Grand D, Laulagnier K, Stella A, Lambeau G, Paillasse M, De Medina P, Monsarrat B, Perret B, Silvente-Poirot S, Poirot M, Record M. |
Journal name |
JLR
|
Publication year |
2010 |
Sample |
Basophilic leukemia cells |
Sample name |
RBL-2H3 |
Isolation/purification methods |
Differential centrifugation Sucrose density gradient |
Flotation density |
-
|
Molecules identified in the study |
Protein Lipids |
Methods used in the study |
Western blotting Gas chromatography Thin layer chromatography Mass spectrometry [Qstar XL] FACS |
|
|
2 |
Experiment ID |
15 |
ISEV standards |
✔
EM
|
EV Biophysical techniques |
✘
|
EV Cytosolic markers |
✔
CD63
|
EV Membrane markers |
✘
|
EV Negative markers |
✘
|
EV Particle analysis
|
|
Identified molecule |
mrna
|
Identification method |
Microarray
|
PubMed ID |
17486113
|
Organism |
Mus musculus Homo sapiens |
Experiment description |
Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells. |
Authors |
Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO |
Journal name |
NCB
|
Publication year |
2007 |
Sample |
Mast cells |
Sample name |
MC9 Bone marrow-derived mast cells HMC-1 |
Isolation/purification methods |
Filtration Ultracentrifugation Sucrose density gradient |
Flotation density |
1.11-1.21 g/mL
|
Molecules identified in the study |
Protein mRNA miRNA |
Methods used in the study |
Mass spectrometry [MALDI TOF] Western blotting Microarray miRCURY LNA Array |
|
|
3 |
Experiment ID |
263 |
ISEV standards |
✘
|
EV Biophysical techniques |
✘
|
EV Cytosolic markers |
✔
CD63|CD9
|
EV Membrane markers |
✘
|
EV Negative markers |
✘
|
EV Particle analysis
|
|
Identified molecule |
protein
|
Identification method |
Mass spectrometry
|
PubMed ID |
25242146
|
Organism |
Mus musculus |
Experiment description |
Extracellular Vesicles from Neural Stem Cells Transfer IFN-γ via Ifngr1 to Activate Stat1 Signaling in Target Cells |
Authors |
Chiara Cossetti, Nunzio Iraci, Tim R. Mercer, Tommaso Leonardi, Emanuele Alpi, Denise Drago, Clara Alfaro-Cervello, Harpreet K. Saini, Matthew P. Davis, Julia Schaeffer, Beatriz Vega, Matilde Stefanini, CongJian Zhao, Werner Muller, Jose Manuel Garcia-Verdugo, Suresh Mathivanan, Angela Bachi, Anton J. Enright, John S. Mattick, Stefano Pluchino |
Journal name |
Molecular Cell
|
Publication year |
2014 |
Sample |
Neural stem cells |
Sample name |
NPCs - Th1 treated |
Isolation/purification methods |
Differential centrifugation Ultracentrifugation Sucrose density gradient |
Flotation density |
1.13-1.20 g/mL
|
Molecules identified in the study |
Protein |
Methods used in the study |
Western blotting Mass spectrometry |
|
|
4 |
Experiment ID |
33 |
ISEV standards |
✔
EM|IEM
|
EV Biophysical techniques |
✔
Alix|TSG101
|
EV Cytosolic markers |
✘
|
EV Membrane markers |
✘
|
EV Negative markers |
✘
|
EV Particle analysis
|
|
Identified molecule |
protein
|
Identification method |
Mass spectrometry
|
PubMed ID |
21136642
|
Organism |
Mus musculus |
Experiment description |
Oligodendrocytes secrete exosomes containing major myelin and stress-protective proteins: Trophic support for axons? |
Authors |
Kramer-Albers EM, Bretz N, Tenzer S, Winterstein C, Mobius W, Berger H, Nave KA, Schild H, Trotter J |
Journal name |
PROTEOMICS_CL
|
Publication year |
2007 |
Sample |
Oligodendrocytes |
Sample name |
Oligodendrocytes Oli-neu |
Isolation/purification methods |
Differential centrifugation Sucrose density gradient |
Flotation density |
1.10-1.14 g/mL
|
Molecules identified in the study |
Protein |
Methods used in the study |
Mass spectrometry [QTOF] Western blotting Immunoelectron Microscopy |
|
|
Protein-protein interactions for Fabp5 |
|
Protein Interactor |
ExoCarta ID |
Identification method |
PubMed |
Species |
No interactions are found.
|
|
Pathways in which Fabp5 is involved |
|
|
|