Gene description for Krt84
Gene name keratin 84
Gene symbol Krt84
Other names/aliases AV235125
HRb-1
Krt2-16
Krt2-3
Species Mus musculus
 Database cross references - Krt84
ExoCarta ExoCarta_16680
Vesiclepedia VP_16680
Entrez Gene 16680
UniProt Q99M73  
 Krt84 identified in sEVs derived from the following tissue/cell type
Oligodendrocytes 21136642    
 Gene ontology annotations for Krt84
Molecular Function
    structural constituent of skin epidermis GO:0030280 IBA
    structural constituent of skin epidermis GO:0030280 IDA
Biological Process
    keratinization GO:0031424 IBA
    intermediate filament organization GO:0045109 IBA
    regulation of keratinocyte differentiation GO:0045616 IDA
Subcellular Localization
    keratin filament GO:0045095 IBA
    keratin filament GO:0045095 IEA
    keratin filament GO:0045095 ISO
    intermediate filament cytoskeleton GO:0045111 IDA
 Experiment description of studies that identified Krt84 in sEVs
1
Experiment ID 33
MISEV standards
✔
EM|IEM
Biophysical techniques
✔
Alix|TSG101
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 21136642    
Organism Mus musculus
Experiment description Oligodendrocytes secrete exosomes containing major myelin and stress-protective proteins: Trophic support for axons?
Authors "Kramer-Albers EM, Bretz N, Tenzer S, Winterstein C, Mobius W, Berger H, Nave KA, Schild H, Trotter J"
Journal name PROTEOMICS_CL
Publication year 2007
Sample Oligodendrocytes
Sample name Oligodendrocytes
Oli-neu
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.10-1.14 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
Western blotting
Immunoelectron Microscopy
 Protein-protein interactions for Krt84
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Ercc4  
Co-fractionation Mus musculus
View the network image/svg+xml
 Pathways in which Krt84 is involved
PathwayEvidenceSource
Developmental Biology IEA Reactome
Formation of the cornified envelope IEA Reactome
Keratinization IEA Reactome





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