Gene description for CFD
Gene name complement factor D (adipsin)
Gene symbol CFD
Other names/aliases ADIPSIN
ADN
DF
PFD
Species Homo sapiens
 Database cross references - CFD
ExoCarta ExoCarta_1675
Vesiclepedia VP_1675
Entrez Gene 1675
HGNC 2771
MIM 134350
UniProt P00746  
 CFD identified in sEVs derived from the following tissue/cell type
Urine 19056867    
 Gene ontology annotations for CFD
Molecular Function
    serine-type endopeptidase activity GO:0004252 IBA
    serine-type endopeptidase activity GO:0004252 TAS
    serine-type peptidase activity GO:0008236 TAS
Biological Process
    proteolysis GO:0006508 IEA
    complement activation GO:0006956 TAS
    complement activation, alternative pathway GO:0006957 TAS
    response to bacterium GO:0009617 IEA
    protein maturation GO:0051604 IBA
Subcellular Localization
    extracellular region GO:0005576 TAS
    extracellular space GO:0005615 IBA
    platelet alpha granule lumen GO:0031093 TAS
    secretory granule lumen GO:0034774 TAS
    extracellular exosome GO:0070062 HDA
    ficolin-1-rich granule lumen GO:1904813 TAS
 Experiment description of studies that identified CFD in sEVs
1
Experiment ID 63
MISEV standards
Biophysical techniques
AQP2
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19056867    
Organism Homo sapiens
Experiment description Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors "Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA"
Journal name JASN
Publication year 2009
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
 Protein-protein interactions for CFD
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 HNRNPH1 3187
Affinity Capture-RNA Homo sapiens
2 SERPINF2 5345
Reconstituted Complex Homo sapiens
3 ALB 213
Affinity Capture-MS Homo sapiens
View the network image/svg+xml



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