Gene description for GIMAP7
Gene name GTPase, IMAP family member 7
Gene symbol GIMAP7
Other names/aliases IAN7
hIAN7
Species Homo sapiens
 Database cross references - GIMAP7
ExoCarta ExoCarta_168537
Entrez Gene 168537
HGNC 22404
UniProt Q8NHV1  
 GIMAP7 identified in exosomes derived from the following tissue/cell type
Hepatocytes 26054723    
 Gene ontology annotations for GIMAP7
Molecular Function
    GTPase activity GO:0003924 IDA
    protein homodimerization activity GO:0042803 IPI
    protein binding GO:0005515 IPI
    GTP binding GO:0005525 IDA
Biological Process
    metabolic process GO:0008152 IDA
Subcellular Localization
    lipid particle GO:0005811 IDA
    cytoplasm GO:0005737 IEA
 Experiment description of studies that identified GIMAP7 in exosomes
1
Experiment ID 237
ISEV standards
EM
EV Biophysical techniques
TSG101|Alix|HSC70|GAPDH
EV Cytosolic markers
EV Membrane markers
HSP90B1
EV Negative markers
qNano
EV Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
 Protein-protein interactions for GIMAP7
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which GIMAP7 is involved
No pathways found





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