Gene description for Psmb9
Gene name proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2)
Gene symbol Psmb9
Other names/aliases Lmp-2
Lmp2
Species Mus musculus
 Database cross references - Psmb9
ExoCarta ExoCarta_16912
Vesiclepedia VP_16912
Entrez Gene 16912
UniProt P28076  
 Psmb9 identified in sEVs derived from the following tissue/cell type
Fibroblasts 23260141    
 Gene ontology annotations for Psmb9
Molecular Function
    endopeptidase activity GO:0004175 IBA
    threonine-type endopeptidase activity GO:0004298 IEA
    proteasome binding GO:0070628 ISO
Biological Process
    response to bacterium GO:0009617 IEP
    antigen processing and presentation GO:0019882 IDA
    antigen processing and presentation GO:0019882 IMP
    proteasome-mediated ubiquitin-dependent protein catabolic process GO:0043161 IBA
    proteolysis involved in protein catabolic process GO:0051603 IEA
    regulation of cysteine-type endopeptidase activity GO:2000116 ISO
Subcellular Localization
    proteasome complex GO:0000502 ISO
    nucleus GO:0005634 IBA
    nucleoplasm GO:0005654 TAS
    cytosol GO:0005829 IBA
    cytosol GO:0005829 ISO
    cytosol GO:0005829 TAS
    proteasome core complex GO:0005839 IDA
    proteasome core complex, beta-subunit complex GO:0019774 IBA
    proteasome core complex, beta-subunit complex GO:0019774 ISS
    spermatoproteasome complex GO:1990111 IDA
 Experiment description of studies that identified Psmb9 in sEVs
1
Experiment ID 210
MISEV standards
EM
Biophysical techniques
CD81|FLOT1
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23260141    
Organism Mus musculus
Experiment description Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration.
Authors "Luga V, Zhang L, Viloria-Petit AM, Ogunjimi AA, Inanlou MR, Chiu E, Buchanan M, Hosein AN, Basik M, Wrana JL."
Journal name Cell
Publication year 2012
Sample Fibroblasts
Sample name Normal-Fibroblasts (L cells)
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Psmb9
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Psmb9 is involved
PathwayEvidenceSource
Metabolism of proteins IEA Reactome
Post-translational protein modification IEA Reactome
Proteasome assembly IEA Reactome





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