Gene description for Elovl6
Gene name ELOVL family member 6, elongation of long chain fatty acids (yeast)
Gene symbol Elovl6
Other names/aliases C77826
FAE
LCE
Species Mus musculus
 Database cross references - Elovl6
ExoCarta ExoCarta_170439
Vesiclepedia VP_170439
Entrez Gene 170439
UniProt Q920L5  
 Elovl6 identified in sEVs derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Elovl6
Molecular Function
    fatty acid elongase activity GO:0009922 IBA
    fatty acid elongase activity GO:0009922 IEA
    fatty acid elongase activity GO:0009922 ISO
    acyltransferase activity, transferring groups other than amino-acyl groups GO:0016747 IDA
Biological Process
    unsaturated fatty acid biosynthetic process GO:0006636 IEA
    fatty acid elongation, saturated fatty acid GO:0019367 IBA
    fatty acid elongation, saturated fatty acid GO:0019367 ISO
    fatty acid elongation, saturated fatty acid GO:0019367 ISS
    sphingolipid biosynthetic process GO:0030148 IBA
    fatty acid elongation GO:0030497 IDA
    fatty acid elongation, monounsaturated fatty acid GO:0034625 IBA
    fatty acid elongation, monounsaturated fatty acid GO:0034625 IEA
    fatty acid elongation, monounsaturated fatty acid GO:0034625 ISO
    fatty acid elongation, polyunsaturated fatty acid GO:0034626 IBA
    long-chain fatty-acyl-CoA biosynthetic process GO:0035338 IEA
    long-chain fatty acid biosynthetic process GO:0042759 ISO
    long-chain fatty acid biosynthetic process GO:0042759 ISS
    very long-chain fatty acid biosynthetic process GO:0042761 IBA
    very long-chain fatty acid biosynthetic process GO:0042761 IEA
    positive regulation of cold-induced thermogenesis GO:0120162 IMP
Subcellular Localization
    endoplasmic reticulum GO:0005783 ISO
    endoplasmic reticulum membrane GO:0005789 IBA
    endoplasmic reticulum membrane GO:0005789 IDA
    fatty acid elongase complex GO:0009923 IEA
    fatty acid elongase complex GO:0009923 ISO
 Experiment description of studies that identified Elovl6 in sEVs
1
Experiment ID 15
MISEV standards
EM
Biophysical techniques
CD63
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors "Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO"
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Elovl6
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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