Gene description for Olfr78
Gene name olfactory receptor 78
Gene symbol Olfr78
Other names/aliases 4633402A21Rik
MOL2.3
MOR18-2
Or51e2
PSGR
RA1c
Species Mus musculus
 Database cross references - Olfr78
ExoCarta ExoCarta_170639
Vesiclepedia VP_170639
Entrez Gene 170639
UniProt Q8VBV9  
 Olfr78 identified in sEVs derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Olfr78
Molecular Function
    nuclear steroid receptor activity GO:0003707 ISO
    nuclear steroid receptor activity GO:0003707 ISS
    G protein-coupled receptor activity GO:0004930 IEA
    olfactory receptor activity GO:0004984 IBA
    olfactory receptor activity GO:0004984 ISA
    olfactory receptor activity GO:0004984 ISO
    olfactory receptor activity GO:0004984 ISS
    signaling receptor activity GO:0038023 IDA
Biological Process
    G protein-coupled receptor signaling pathway GO:0007186 ISA
    adenylate cyclase-activating G protein-coupled receptor signaling pathway GO:0007189 ISO
    adenylate cyclase-activating G protein-coupled receptor signaling pathway GO:0007189 ISS
    sensory perception of smell GO:0007608 ISA
    sensory perception of smell GO:0007608 ISS
    cell migration GO:0016477 ISO
    cell migration GO:0016477 ISS
    melanocyte differentiation GO:0030318 ISO
    melanocyte differentiation GO:0030318 ISS
    steroid hormone receptor signaling pathway GO:0043401 ISO
    steroid hormone receptor signaling pathway GO:0043401 ISS
    positive regulation of blood pressure GO:0045777 IMP
    detection of chemical stimulus involved in sensory perception of smell GO:0050911 IEA
    cellular response to fatty acid GO:0071398 IDA
    melanocyte proliferation GO:0097325 ISO
    melanocyte proliferation GO:0097325 ISS
    positive regulation of renin secretion into blood stream GO:1900135 IMP
Subcellular Localization
    plasma membrane GO:0005886 IBA
    plasma membrane GO:0005886 IDA
    plasma membrane GO:0005886 ISO
    plasma membrane GO:0005886 ISS
    membrane GO:0016020 ISA
    early endosome membrane GO:0031901 ISO
    early endosome membrane GO:0031901 ISS
    intracellular organelle GO:0043229 ISO
 Experiment description of studies that identified Olfr78 in sEVs
1
Experiment ID 15
MISEV standards
EM
Biophysical techniques
CD63
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors "Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO"
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Olfr78
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Olfr78 is involved
PathwayEvidenceSource
Olfactory Signaling Pathway IEA Reactome
Sensory Perception IEA Reactome





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