Gene description for Olfr78
Gene name olfactory receptor 78
Gene symbol Olfr78
Other names/aliases 4633402A21Rik
MOL2.3
MOR18-2
Or51e2
PSGR
RA1c
Species Mus musculus
 Database cross references - Olfr78
ExoCarta ExoCarta_170639
Entrez Gene 170639
UniProt Q8VBV9  
 Olfr78 identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Olfr78
Molecular Function
    G-protein coupled receptor activity GO:0004930 IEA
    signaling receptor activity GO:0038023 IDA
    signal transducer activity GO:0004871 IEA
    steroid hormone receptor activity GO:0003707 ISO
    olfactory receptor activity GO:0004984 ISS
Biological Process
    steroid hormone mediated signaling pathway GO:0043401 ISO
    detection of chemical stimulus involved in sensory perception of smell GO:0050911 ISS
    positive regulation of blood pressure GO:0045777 IMP
    sensory perception of smell GO:0007608 ISS
    positive regulation of renin secretion into blood stream GO:1900135 IMP
    signal transduction GO:0007165 ISS
    cellular response to fatty acid GO:0071398 IDA
    response to stimulus GO:0050896 IEA
    G-protein coupled receptor signaling pathway GO:0007186 ISA
Subcellular Localization
    integral component of plasma membrane GO:0005887 ISS
    membrane GO:0016020 IEA
    integral component of membrane GO:0016021 ISA
    plasma membrane GO:0005886 ISO
 Experiment description of studies that identified Olfr78 in exosomes
1
Experiment ID 15
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Olfr78
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Olfr78 is involved
PathwayEvidenceSource
Olfactory Signaling Pathway IEA Reactome





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