Gene description for Slco1a2
Gene name solute carrier organic anion transporter family, member 1A2
Gene symbol Slco1a2
Other names/aliases Oatp2
Slc21a5
Slco1a4
Species Rattus norvegicus
 Database cross references - Slco1a2
ExoCarta ExoCarta_170698
Vesiclepedia VP_170698
Entrez Gene 170698
UniProt O35913  
 Slco1a2 identified in sEVs derived from the following tissue/cell type
Hepatocytes 19367702    
 Gene ontology annotations for Slco1a2
Molecular Function
    organic anion transmembrane transporter activity GO:0008514 IDA
    organic anion transmembrane transporter activity GO:0008514 ISO
    bile acid transmembrane transporter activity GO:0015125 IBA
    bile acid transmembrane transporter activity GO:0015125 IDA
    sodium-independent organic anion transmembrane transporter activity GO:0015347 IBA
    transmembrane transporter activity GO:0022857 IEA
    transmembrane transporter activity GO:0022857 ISO
Biological Process
    monoatomic ion transport GO:0006811 IEA
    monoatomic anion transport GO:0006820 ISO
    bile acid and bile salt transport GO:0015721 IBA
    sodium-independent organic anion transport GO:0043252 IBA
    sodium-independent organic anion transport GO:0043252 IDA
    response to estrogen GO:0043627 IEP
    transmembrane transport GO:0055085 IEA
    cellular response to xenobiotic stimulus GO:0071466 IEP
Subcellular Localization
    plasma membrane GO:0005886 IEA
    plasma membrane GO:0005886 ISO
    basal plasma membrane GO:0009925 IDA
    basal plasma membrane GO:0009925 ISO
    membrane GO:0016020 ISO
    basolateral plasma membrane GO:0016323 IBA
 Experiment description of studies that identified Slco1a2 in sEVs
1
Experiment ID 35
MISEV standards
CEM
Biophysical techniques
TSG101|Alix|CD81|CD63
Enriched markers
HSPA5
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19367702    
Organism Rattus norvegicus
Experiment description Characterization and Comprehensive Proteome Profiling of Exosomes Secreted by Hepatocytes.
Authors "Conde-Vancells J, Rodriguez-Suarez E, Embade N, Gil D, Matthiesen R, Valle M, Elortza F, Lu SC, Mato JM, Falcon-Perez JM"
Journal name JPR
Publication year 2008
Sample Hepatocytes
Sample name Hepatocytes
Isolation/purification methods Differential centrifugation
Filtration
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
Western blotting
 Protein-protein interactions for Slco1a2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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