Gene description for Atp13a1
Gene name ATPase type 13A1
Gene symbol Atp13a1
Other names/aliases Atp13a
Cgi152
catp
Species Mus musculus
 Database cross references - Atp13a1
ExoCarta ExoCarta_170759
Vesiclepedia VP_170759
Entrez Gene 170759
UniProt Q9EPE9  
 Atp13a1 identified in sEVs derived from the following tissue/cell type
Pancreatic cells 19351151    
 Gene ontology annotations for Atp13a1
Molecular Function
    ATP binding GO:0005524 IEA
    P-type ion transporter activity GO:0015662 IBA
    ATP hydrolysis activity GO:0016887 IEA
    ATPase-coupled monoatomic cation transmembrane transporter activity GO:0019829 IBA
    metal ion binding GO:0046872 IEA
    P-type transmembrane transporter activity GO:0140358 IEA
    membrane protein dislocase activity GO:0140567 IBA
    membrane protein dislocase activity GO:0140567 ISO
    membrane protein dislocase activity GO:0140567 ISS
Biological Process
    intracellular calcium ion homeostasis GO:0006874 IBA
    protein transport GO:0015031 IEA
    transmembrane transport GO:0055085 IBA
    transmembrane transport GO:0055085 IEA
    extraction of mislocalized protein from ER membrane GO:0140569 IBA
    extraction of mislocalized protein from ER membrane GO:0140569 ISO
    extraction of mislocalized protein from ER membrane GO:0140569 ISS
Subcellular Localization
    endoplasmic reticulum membrane GO:0005789 IBA
    endoplasmic reticulum membrane GO:0005789 IDA
 Experiment description of studies that identified Atp13a1 in sEVs
1
Experiment ID 188
MISEV standards
EM
Biophysical techniques
GAPDH|UCHL1|HSP90
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19351151    
Organism Mus musculus
Experiment description Characterization of vesicles secreted from insulinoma NIT-1 cells.
Authors "Lee HS, Jeong J, Lee KJ."
Journal name J Proteome Res
Publication year 2009
Sample Pancreatic cells
Sample name Pancreatic beta cell (NIT-1)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Atp13a1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Scn9a  
Co-fractionation Mus musculus
2 Atp2c1  
Co-fractionation Mus musculus
3 Sel1l  
Co-fractionation Mus musculus
4 Tmem173  
Proximity Label-MS Mus musculus
View the network image/svg+xml
 Pathways in which Atp13a1 is involved
PathwayEvidenceSource
Ion channel transport IEA Reactome
Ion transport by P-type ATPases IEA Reactome
Transport of small molecules IEA Reactome





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