Gene description for Olr59
Gene name olfactory receptor 59
Gene symbol Olr59
Other names/aliases Olfr78
Or51e2
RA1c
Species Rattus norvegicus
 Database cross references - Olr59
ExoCarta ExoCarta_170816
Vesiclepedia VP_170816
Entrez Gene 170816
UniProt O88628  
 Olr59 identified in sEVs derived from the following tissue/cell type
Pancreatic cancer cells 20124479    
Pancreatic cancer cells 20124479    
 Gene ontology annotations for Olr59
Molecular Function
    nuclear steroid receptor activity GO:0003707 IEA
    nuclear steroid receptor activity GO:0003707 ISO
    nuclear steroid receptor activity GO:0003707 ISS
    G protein-coupled receptor activity GO:0004930 IEA
    olfactory receptor activity GO:0004984 IBA
    olfactory receptor activity GO:0004984 IEA
    olfactory receptor activity GO:0004984 ISO
    olfactory receptor activity GO:0004984 ISS
    signaling receptor activity GO:0038023 ISO
    signaling receptor activity GO:0038023 ISS
Biological Process
    adenylate cyclase-activating G protein-coupled receptor signaling pathway GO:0007189 IEA
    adenylate cyclase-activating G protein-coupled receptor signaling pathway GO:0007189 ISO
    adenylate cyclase-activating G protein-coupled receptor signaling pathway GO:0007189 ISS
    cell migration GO:0016477 IEA
    cell migration GO:0016477 ISO
    cell migration GO:0016477 ISS
    melanocyte differentiation GO:0030318 IEA
    melanocyte differentiation GO:0030318 ISO
    melanocyte differentiation GO:0030318 ISS
    steroid hormone receptor signaling pathway GO:0043401 IEA
    steroid hormone receptor signaling pathway GO:0043401 ISO
    steroid hormone receptor signaling pathway GO:0043401 ISS
    positive regulation of blood pressure GO:0045777 IEA
    positive regulation of blood pressure GO:0045777 ISO
    positive regulation of blood pressure GO:0045777 ISS
    detection of chemical stimulus involved in sensory perception of smell GO:0050911 IEA
    cellular response to fatty acid GO:0071398 IEA
    cellular response to fatty acid GO:0071398 ISO
    cellular response to fatty acid GO:0071398 ISS
    melanocyte proliferation GO:0097325 IEA
    melanocyte proliferation GO:0097325 ISO
    melanocyte proliferation GO:0097325 ISS
    positive regulation of renin secretion into blood stream GO:1900135 IEA
    positive regulation of renin secretion into blood stream GO:1900135 ISO
    positive regulation of renin secretion into blood stream GO:1900135 ISS
Subcellular Localization
    plasma membrane GO:0005886 IBA
    plasma membrane GO:0005886 IEA
    plasma membrane GO:0005886 ISO
    plasma membrane GO:0005886 ISS
    early endosome membrane GO:0031901 IEA
    early endosome membrane GO:0031901 ISO
    early endosome membrane GO:0031901 ISS
 Experiment description of studies that identified Olr59 in sEVs
1
Experiment ID 92
MISEV standards
EM
Biophysical techniques
HSP70|GAPDH|CD9|CD151
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 20124479    
Organism Rattus norvegicus
Experiment description Cell surface tetraspanin Tspan8 contributes to molecular pathways of exosome-induced endothelial cell activation.
Authors "Nazarenko I, Rana S, Baumann A, McAlear J, Hellwig A, Trendelenburg M, Lochnit G, Preissner KT, Zoller M."
Journal name CR
Publication year 2010
Sample Pancreatic cancer cells
Sample name AS
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.14-1.17 g/mL
Molecules identified in the study Protein
mRNA
Methods used in the study RT-PCR
Western blotting
RatRef-12 Microarray
FACS
Mass spectrometry [MALDI TOF]
2
Experiment ID 93
MISEV standards
EM
Biophysical techniques
HSP70|GAPDH|CD9|CD151
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 20124479    
Organism Rattus norvegicus
Experiment description Cell surface tetraspanin Tspan8 contributes to molecular pathways of exosome-induced endothelial cell activation.
Authors "Nazarenko I, Rana S, Baumann A, McAlear J, Hellwig A, Trendelenburg M, Lochnit G, Preissner KT, Zoller M."
Journal name CR
Publication year 2010
Sample Pancreatic cancer cells
Sample name AS-Tspan8
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.14-1.17 g/mL
Molecules identified in the study Protein
mRNA
Methods used in the study RT-PCR
Western blotting
 Protein-protein interactions for Olr59
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Olr59 is involved
No pathways found





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