Gene description for Olr59
Gene name olfactory receptor 59
Gene symbol Olr59
Other names/aliases Olfr78
Or51e2
RA1c
Species Rattus norvegicus
 Database cross references - Olr59
ExoCarta ExoCarta_170816
Entrez Gene 170816
UniProt O88628  
 Olr59 identified in exosomes derived from the following tissue/cell type
Pancreatic cancer cells 20124479    
Pancreatic cancer cells 20124479    
 Gene ontology annotations for Olr59
Molecular Function
    olfactory receptor activity GO:0004984 ISS
    steroid hormone receptor activity GO:0003707 ISS
    signaling receptor activity GO:0038023 ISS
    G-protein coupled receptor activity GO:0004930 IEA
Biological Process
    detection of chemical stimulus involved in sensory perception of smell GO:0050911 ISS
    positive regulation of blood pressure GO:0045777 ISS
    steroid hormone mediated signaling pathway GO:0043401 ISS
    positive regulation of renin secretion into blood stream GO:1900135 ISS
    cellular response to fatty acid GO:0071398 ISS
    G-protein coupled receptor signaling pathway GO:0007186 IEA
Subcellular Localization
    integral component of membrane GO:0016021 IEA
    plasma membrane GO:0005886 ISS
 Experiment description of studies that identified Olr59 in exosomes
1
Experiment ID 92
ISEV standards
EM
EV Biophysical techniques
HSP70|GAPDH
EV Cytosolic markers
CD9|CD151
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 20124479    
Organism Rattus norvegicus
Experiment description Cell surface tetraspanin Tspan8 contributes to molecular pathways of exosome-induced endothelial cell activation.
Authors Nazarenko I, Rana S, Baumann A, McAlear J, Hellwig A, Trendelenburg M, Lochnit G, Preissner KT, Zoller M.
Journal name CR
Publication year 2010
Sample Pancreatic cancer cells
Sample name AS
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.14-1.17 g/mL
Molecules identified in the study Protein
mRNA
Methods used in the study RT-PCR
Western blotting
RatRef-12 Microarray
FACS
Mass spectrometry [MALDI TOF]
2
Experiment ID 93
ISEV standards
EM
EV Biophysical techniques
HSP70|GAPDH
EV Cytosolic markers
CD9|CD151
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 20124479    
Organism Rattus norvegicus
Experiment description Cell surface tetraspanin Tspan8 contributes to molecular pathways of exosome-induced endothelial cell activation.
Authors Nazarenko I, Rana S, Baumann A, McAlear J, Hellwig A, Trendelenburg M, Lochnit G, Preissner KT, Zoller M.
Journal name CR
Publication year 2010
Sample Pancreatic cancer cells
Sample name AS-Tspan8
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.14-1.17 g/mL
Molecules identified in the study Protein
mRNA
Methods used in the study RT-PCR
Western blotting
 Protein-protein interactions for Olr59
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Olr59 is involved
No pathways found





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