Gene description for Ilk
Gene name	integrin-linked kinase
Gene symbol	Ilk
Other names/aliases	-
Species	Rattus norvegicus
Database cross references - Ilk
ExoCarta	ExoCarta_170922
Entrez Gene	170922
UniProt	Q99J82
Ilk identified in exosomes derived from the following tissue/cell type
Adipocytes	25998041
Reticulocytes	21828046

Gene ontology annotations for Ilk

Molecular Function     protein kinase activity GO:0004672 IDA     protein domain specific binding GO:0019904 IC     ATP binding GO:0005524 IEA     protein kinase binding GO:0019901 ISO     protein binding GO:0005515 IPI     SH3 domain binding GO:0017124 IDA     signal transducer activity GO:0004871 IDA     integrin binding GO:0005178 IPI     protein serine/threonine kinase activity GO:0004674 ISO Biological Process     negative regulation of neuron apoptotic process GO:0043524 IMP     positive regulation of cell migration GO:0030335 IMP     integrin-mediated signaling pathway GO:0007229 ISO     extracellular fibril organization GO:0043206 IMP     regulation of cell growth GO:0001558 IMP     negative regulation of smooth muscle cell proliferation GO:0048662 IMP     protein kinase B signaling GO:0043491 ISO     Schwann cell development GO:0014044 ISO     fibroblast migration GO:0010761 ISO     negative regulation of apoptotic process GO:0043066 IMP     regulation of actin cytoskeleton organization GO:0032956 IMP     nerve development GO:0021675 ISO     negative regulation of protein kinase activity GO:0006469 IMP     substrate adhesion-dependent cell spreading GO:0034446 ISO     positive regulation of phosphorylation GO:0042327 ISO     negative regulation of cardiac muscle cell apoptotic process GO:0010667 IMP     positive regulation of MAP kinase activity GO:0043406 IMP     peptidyl-serine phosphorylation GO:0018105 ISO     myelination in peripheral nervous system GO:0022011 ISO     platelet aggregation GO:0070527 ISO     positive regulation of BMP signaling pathway GO:0030513 ISO     cell cycle arrest GO:0007050 IMP     positive regulation of transcription, DNA-templated GO:0045893 ISO     protein heterooligomerization GO:0051291 IPI     cell aging GO:0007569 IMP     positive regulation of canonical Wnt signaling pathway GO:0090263 ISO     positive regulation of cell proliferation GO:0008284 ISO     positive regulation of osteoblast differentiation GO:0045669 ISO     cell projection organization GO:0030030 ISO     positive regulation of MAPK cascade GO:0043410 IMP     myelin assembly GO:0032288 IMP     branching involved in ureteric bud morphogenesis GO:0001658 ISO     establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 ISO     positive regulation of dendrite morphogenesis GO:0050775 IMP     positive regulation of myoblast differentiation GO:0045663 IMP     positive regulation of axonogenesis GO:0050772 IMP     positive regulation of protein kinase B signaling GO:0051897 IMP     neuron projection morphogenesis GO:0048812 IMP     positive regulation of axon extension GO:0045773 IMP     protein phosphorylation GO:0006468 ISO     negative regulation of smooth muscle cell migration GO:0014912 IMP     negative regulation of neural precursor cell proliferation GO:2000178 ISO     positive regulation of cell-matrix adhesion GO:0001954 IMP Subcellular Localization     membrane GO:0016020 ISO     costamere GO:0043034 IDA     plasma membrane GO:0005886 IEA     extracellular matrix GO:0031012 IMP     nucleoplasm GO:0005654 ISO     axon GO:0030424 IDA     focal adhesion GO:0005925 ISO     cytoplasm GO:0005737 ISO     terminal bouton GO:0043195 IDA     dendritic shaft GO:0043198 IDA     cell-cell junction GO:0005911 IDA     stress fiber GO:0001725 IDA     lamellipodium GO:0030027 ISO     neuronal cell body GO:0043025 IDA     sarcomere GO:0030017 IEA     intracellular GO:0005622 ISO     protein complex GO:0043234 IDA     cell junction GO:0030054 ISO